ReviewJournal of the Society for Cardiovascular Angiography & Interventions2025
Time-Dependent Changes in the Coronary Circulation Triggered by CTO Revascularization: Insights From Intracoronary Physiology.
Review in Journal of the Society for Cardiovascular Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Background: Physiological changes in the coronary circulation associated with percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) remain largely unknown. This systematic review and meta-analysis aimed to investigate physiological changes in the CTO and donor vessel before and immediately after PCI, as well as at follow-up. Methods: A comprehensive search of PubMed/MEDLINE and Embase identified relevant studies. The primary end point was the mean difference (MD) between fractional flow reserve myocardium (FFR Results: A total of 17 studies were included. The myocardial blood flow in the donor vessel increased after CTO revascularization (FFR Conclusion: Available evidence suggests that CTO revascularization leads to an immediate and long-term improvement in blood supply to downstream myocardium, mediated in part by a favorable time-dependent shift in epicardial vessel, collateral, and microcirculatory function.
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