ArticleJournal of general and family medicine2025
Calcineurin-inhibitor induced pain syndrome due to interaction with clarithromycin: A case report.
Article in Journal of general and family medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Calcineurin-inhibitor induced pain syndrome due to interaction with clarithromycin: A case report.Journal of general and family medicine · 2025Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Calcineurin inhibitor-induced pain syndrome (CIPS) is a rare but serious condition characterized by severe lower leg pain, often associated with elevated tacrolimus (TAC) levels. We report the case of a 57-year-old woman with rheumatoid arthritis (RA) who developed CIPS following a drug interaction between TAC and clarithromycin (CAM), a common macrolide antibiotic. Discontinuation of TAC led to a rapid resolution of symptoms. This case highlights the importance of monitoring TAC levels and being cautious of drug interactions, especially in primary care settings, to prevent adverse events like CIPS.
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