Evidence map›Paper›PMID 40061338›Full record

ArticlemedRxiv : the preprint server for health sciences2025

SmART-TBI: A fully remote protocol for a randomized placebo-controlled double-blinded clinical trial for a dietary supplement to improve sleep in Veterans.

Jonathan E Elliott, Savanah J Sicard, Cosette Olivo, Hannah A Cunningham, Arlynn E Ekis, Katherine L Powers, Jessica S Brewer, Jennifer D'Silva, Sarah Happ, Andrea Hildebrand and 2 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Jonathan E ElliottVA Portland Health Care System, Research Service, Portland, OR, USA.ORCID 0000-0002-6992-6851
Savanah J SicardVA Portland Health Care System, Research Service, Portland, OR, USA.
Cosette OlivoVA Portland Health Care System, Research Service, Portland, OR, USA.
Hannah A CunninghamVA Portland Health Care System, Research Service, Portland, OR, USA.ORCID 0000-0001-5093-1741
Arlynn E EkisVA Portland Health Care System, Research Service, Portland, OR, USA.
Katherine L PowersVA Portland Health Care System, Research Service, Portland, OR, USA.
Jessica S BrewerVA Portland Health Care System, Research Service, Portland, OR, USA.
Jennifer D'SilvaVA Portland Health Care System, Research Service, Portland, OR, USA.
Sarah HappVA Portland Health Care System, Research Service, Portland, OR, USA.
Andrea HildebrandOregon Health & Science University - Portland State University, School of Public Health, Biostatistics & Design Program, Portland, OR, USA.
Akiva CohenUniversity of Pennsylvania, Perelman School of Medicine, Anesthesiology and Critical Care Medicine, Philadelphia, PA, USA.
Miranda M LimOregon Health & Science University, Department of Neurology, Portland, OR, USA.ORCID 0000-0003-3876-3196

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Zachary Beattie · 2020 to 2026
$28.6M
CAM Research Training in Neuroscience &StressT32AT002688 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI OKEN, BARRY S, SOUMYANATH, AMALA · 2005 to 2025
$7.2M
BLRD VA I01 BX006155CSRD VA I01 CX002022NCATS NIH HHS UL1 TR002369NCCIH NIH HHS T32 AT002688NIA NIH HHS P30 AG066518RRD VA IK2 RX002947
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is associated with chronic sleep disturbances and cognitive impairment, with limited effective therapeutic strategies. Our previous work showed dietary supplementation with branched chain amino acids (BCAAs; isoleucine, leucine, valine), the primary substrate for

Indexed as

Branched chain amino aciddietary supplementrandomized clinical trialsleep disturbancestraumatic brain injury

Identifiers

PMID40061338
PMCPMC11888520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.