Evidence map›Paper›PMID 40061252›Full record

ArticlePaediatrics & child health2025

Therapeutic Dilemma: Melatonin or not?

Savithiri Ratnapalan, Michael Rieder

Abstract read
In one paragraph

Article in Paediatrics & child health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Savithiri RatnapalanHospital for Sick Children, Toronto, Ontario, Canada.
Michael RiederHospital for Sick Children, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disturbances are common in childhood, especially among neurodivergent children. There are few proven therapeutic options. Melatonin is a hormone that is critical to the normal human sleep cycle. Melatonin therapy has been proven to be effective in adults with jet lag and there is emerging evidence that it may be of value when used in low doses for neurodivergent children. There is however no evidence that melatonin is of utility in addressing sleep problems in otherwise well children.

Indexed as

AutismChildrenMelatoninSleep

Identifiers

PMID40061252
PMCPMC11885872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.