Evidence map›Paper›PMID 40061180›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

A novel method for objective quantification of apathy based on gaze and physiological reactivity to stimuli presented in a virtual reality environment.

Ramit Ravona-Springer, Or Koren, Noam Galor, Michal Lapid, Yotam Bahat, Ronen Fluss, Meytal Wilf, Shlomit Zorani, Uri Rosenblum, Michal Schnaider Beeri and 1 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ramit Ravona-SpringerGeriatric Psychiatry and Memory Unit, Sheba Tel-HaShomer Medical Center Tel Aviv Israel.
Or KorenCenter of Advanced Technologies in Rehabilitation Sheba Tel-HaShomer Medical Center Ramat Gan Israel.
Noam GalorCenter of Advanced Technologies in Rehabilitation Sheba Tel-HaShomer Medical Center Ramat Gan Israel.
Michal LapidThe Joseph Sagol Neuroscience Center Sheba Tel-HaShomer Medical Center Tel Aviv Israel.
Yotam BahatCenter of Advanced Technologies in Rehabilitation Sheba Tel-HaShomer Medical Center Ramat Gan Israel.
Ronen FlussThe Biostatistics and Biomathematics Unit, The Gertner Institute for Health Policy and Epidemiology Sheba Tel-HaShomer Medical Center Ramat Gan Israel.
Meytal WilfCenter of Advanced Technologies in Rehabilitation Sheba Tel-HaShomer Medical Center Ramat Gan Israel.
Shlomit ZoraniThe Joseph Sagol Neuroscience Center Sheba Tel-HaShomer Medical Center Tel Aviv Israel.
Uri RosenblumCenter of Advanced Technologies in Rehabilitation Sheba Tel-HaShomer Medical Center Ramat Gan Israel.
Michal Schnaider BeeriKrieger Klein Alzheimer's Research Center Rutgers Brain Health Institute New Brunswick New Jersey USA.
Meir PlotnikCenter of Advanced Technologies in Rehabilitation Sheba Tel-HaShomer Medical Center Ramat Gan Israel.

Funding

Cognitive and brain imaging correlates of apathy- components in asymptomatic middle aged individuals at high ADRD- riskR21AG080827 · NIA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI RAVONA, RAMIT, SCHNAIDER BEERI, MICHAL · 2023 to 2024
$365k
NIA NIH HHS R21 AG080827
6 · The paper itself

Abstract

introductionWe developed a tool for objective quantification of apathy.

methodsParticipants (

resultsThe sample comprised 14 participants with apathy only, 9 with depression only, 10 with both, 63 with neither, and 1 with missing data. For all emotional stimuli, participants with apathy only showed longer TTFF ( DISCUSSION: Apathy is associated with decreased gaze engagement at emotional stimuli. Highlights: Apathy measurement via questionnaires is limited by subjectivity biases.Apathy measurement via questionnaires is limited by simplistic scoring.We present a novel method for objective measurement of apathy.Gaze characteristics reflect the emotional and cognitive components of apathy.

Indexed as

apathyautonomic nervous systemcognitive component of apathycognitive impairmentdementiaemotional component of apathygazeobjective measurementphysiological reactivitysubjective measurementvirtual reality

Identifiers

PMID40061180
PMCPMC11886987

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.