Evidence map›Paper›PMID 40061154›Full record

ArticleAJPM focus2025

Supporting Access to HIV Pre-Exposure Prophylaxis in a Shifting Financial and Insurance Landscape.

Connor Eichenwald, Robin T Higashi, Timothy P Hogan, Jacqueline Naeem, Julia L Marcus, Douglas Krakower, Ank E Nijhawan

Abstract read
In one paragraph

Article in AJPM focus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Connor EichenwaldUniversity of Texas Southwestern Medical School, Dallas, Texas.
Robin T HigashiPeter O'Donnell School of Public Health, UT Southwestern Medical Center, Dallas, Texas.
Timothy P HoganPeter O'Donnell School of Public Health, UT Southwestern Medical Center, Dallas, Texas.
Jacqueline NaeemParkland Center for Clinical Innovation, Dallas, Texas.
Julia L MarcusDepartment of Population Medicine, Harvard Medical School, Boston, Massachusetts.
Douglas KrakowerDepartment of Population Medicine, Harvard Medical School, Boston, Massachusetts.
Ank E NijhawanDivision of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.

Funding

Trends in Incidence and Prevalence of HIV Diagnoses in a Jail Population in the Southern United StatesR01MH129185 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI Douglas Scott Krakower, Ank Elisabeth Nijhawan · 2022 to 2026
$3.2M
NIMH NIH HHS R01 MH129185
6 · The paper itself

Abstract

Introduction: Implementing HIV pre-exposure prophylaxis in the U.S. is critical to decreasing HIV transmission. However, regional disparities in pre-exposure prophylaxis use exist, with the southern U.S. having the lowest uptake relative to need. Community-based organizations in the South provide pre-exposure prophylaxis to many consumers, including those without health insurance. Methods: The authors convened a community-building pre-exposure prophylaxis summit in April 2023 with representatives from diverse pre-exposure prophylaxis providers, including community-based organizations in Dallas, Texas, to evaluate the impact of recent changes in pre-exposure prophylaxis funding mechanisms on their capabilities to provide pre-exposure prophylaxis. Participants completed surveys ( Results: The authors found that reduced reimbursements from pre-exposure prophylaxis manufacturers have significantly altered the financial health of community-based organizations in Dallas, Texas, and jeopardized their capacity to provide pre-exposure prophylaxis. Community-based organizations reported difficulty in sustainably providing pre-exposure prophylaxis to uninsured clients because of fewer funds to cover unreimbursed costs for pre-exposure prophylaxis care. Many community-based organizations have diverted resources away from client outreach for pre-exposure prophylaxis and toward helping clients to enroll in commercial insurance plans that cover pre-exposure prophylaxis. These changes have further stressed community-based organizations by increasing the time spent by staff on managing prior authorizations for pre-exposure prophylaxis. Despite finding some success with workarounds, community-based organizations described continued financial fragility. Conclusions: These findings suggest that fragmented funding streams jeopardize the ability of these vital organizations to continue providing pre-exposure prophylaxis services in a jurisdiction with high HIV incidence. Potential solutions include enhanced collaboration across community-based organizations and stable financial support from a national pre-exposure prophylaxis program.

Indexed as

340B Programcommunity-based health organizationsHIV Preventionpharmaceutical pricingPrEP

Identifiers

PMID40061154
PMCPMC11889952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.