Evidence map›Paper›PMID 40060908›Full record

ArticleiScience2025

The impact of lymph node dissection on stage I ovarian endometrioid carcinoma: A US-China Comparative Analysis.

Meige Sun, Fei Lin, Jing Shi, Xiang-Guang Wu, Yunyi Liang, Jialing Chen, Qinglei Gao, Shuzhong Yao, Jiangtao Fan, Youguo Chen and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Meige SunDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Fei LinDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jing ShiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiang-Guang WuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yunyi LiangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jialing ChenDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Qinglei GaoDepartment of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shuzhong YaoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jiangtao FanDepartment of Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Youguo ChenDepartment of Gynecology & Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou, China.
Danbo WangDepartment of Gynecologic Oncology, Liaoning Cancer Hospital, Shenyang, China.
Yi HuangDepartment of Gynecologic Oncology, Hubei Cancer Hospital, Wuhan, China.
Liang-Sheng FanDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jun YangThe Key Laboratory of Advanced Interdisciplinary Studies, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wei WangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the prognostic impact of lymph node dissection (LND) in patients with stage I ovarian endometrioid carcinoma (OEC) and aimed to identify the optimal LND range for improved survival. By analyzing data from the Surveillance, Epidemiology, and End Results (SEER) database conducted in USA and NUWA database in China, we found that patients who underwent LND in the SEER cohort exhibited significantly improved long-term survival rates compared to those who did not undergo LND, while the difference was not statistically significant in the NUWA cohort. Cox regression and restricted cubic spline analyses indicated an inverted U-shaped association between the number of LNDs and hazard ratios, identifying 29-34 lymph nodes as the optimal range. This finding suggests that performing LND within this specified range may enhance survival outcomes for patients with stage I OEC.

Indexed as

Clinical findingOncologySurgery

Identifiers

PMID40060908
PMCPMC11889732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.