ArticleACS omega2025
Multi-Microseconds Microbubbles Induced by Nanoseconds Pulsed-Laser Heating of Gold Nano-Particles.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Low-power optical tweezers using large-diameter Gaussian and vortex beams for giant bubble trapping and rotation in fluorescent dye media.Scientific reports · 2026Article
- Nanoparticle enhanced coupled bioheat vapor bubble model and simulation for LITT in breast tumors.Lasers in medical science · 2025Article
- Using high speed visualization to identify variations in the formation and distribution of plasmonic microbubbles.AIP advances · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examines the effect of gold-nanoparticles (GNPs) aggregation on the formation of multimicrosecond water-vapor (WV) microbubbles (MBs) generated by nanosecond pulsed-laser heating of GNPs in water. The MBs' dynamics reveal a "dual-nature" system involving both WV phase change and the release of dissolved gases (DGs). High-speed visualization (216 kfps) captures two distinct stages in the MB lifecycle: an initial fast growth-collapse of the WV phase (multimicrosecond duration), followed by a slow collapse driven by DG release (>milliseconds). A double-exponential function effectively captures these stages, distinguishing WV and DG contributions. The prolonged WV lifetime, which differs significantly from previously reported nanosecond-scale lifetime, is strongly influenced by aggregation effects. This is supported by numerical-modeling of the heat diffusion around a plasmonically heated GNP, where aggregation is assumed to occur prior to the pulsed-laser application. Besides, a correlation found to exist between the WV's lifetime and the DGs' contribution to the overall MBs, the larger the DGs' contribution, the shorter the lifetime of the WV is, which is found to be driven by the increasing likelihood of aggregation. In summary, aggregation can either enhance or suppress plasmonic bubble generation and influence the WV lifetime or DG release. This work demonstrates the feasibility of multimicrosecond WV-MBs, which potentially can offer an extended operational window for various applications, including imaging, diagnostics, and therapeutics, and microfluidic technologies.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.