Evidence map›Paper›PMID 40060766›Full record

ArticleBioengineering & translational medicine2025

Endoluminal photodynamic therapy with a photoreactive stent-based catheter system to treat malignant colorectal obstruction.

Seung Jin Eo, Dae Sung Ryu, Hyeonseung Lee, Ji Won Kim, Song Hee Kim, Jin Hee Noh, Yuri Kim, Seokin Kang, Kun Na, Jung-Hoon Park and 1 more

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Seung Jin EoBiomedical Engineering Research Center, Asan Institute for Life Sciences Asan Medical Center Seoul Republic of Korea.
Dae Sung RyuBiomedical Engineering Research Center, Asan Institute for Life Sciences Asan Medical Center Seoul Republic of Korea.
Hyeonseung LeeDepartment of Biotechnology, Department of Biomedical-Chemical Engineering The Catholic University of Korea Bucheon-si Gyeonggi-do Republic of Korea.
Ji Won KimBiomedical Engineering Research Center, Asan Institute for Life Sciences Asan Medical Center Seoul Republic of Korea.
Song Hee KimBiomedical Engineering Research Center, Asan Institute for Life Sciences Asan Medical Center Seoul Republic of Korea.
Jin Hee NohDepartment of Gastroenterology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea.
Yuri KimDepartment of Gastroenterology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea.
Seokin KangDepartment of Internal Medicine, Ilsan Paik Hospital Inje University College of Medicine Goyang-si Gyeonggi-do Republic of Korea.
Kun NaDepartment of Biotechnology, Department of Biomedical-Chemical Engineering The Catholic University of Korea Bucheon-si Gyeonggi-do Republic of Korea.
Jung-Hoon ParkBiomedical Engineering Research Center, Asan Institute for Life Sciences Asan Medical Center Seoul Republic of Korea.ORCID https://orcid.org/0000-0001-8856-8335
Do Hoon KimDepartment of Gastroenterology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea.

Funding

NCIRD CDC HHS H23 IP000682
6 · The paper itself

Abstract

Photodynamic therapy (PDT) using photosensitizer (PS)-embedded silicone membrane-covered self-expandable metallic stents (SEMSs) can function in palliative therapeutic option for malignant gastrointestinal tract obstruction. However, stent-related complications should be considered, and accurate delivery of light sources is technically difficult. Here, a Chlorin e6 (Ce6)-an embedded stent-based catheter is developed to improve its therapeutic efficacy and safety. PDT using Ce6-embedded stent successfully induced cell death of colorectal cancer cell line. PDT-treated liver tissues showed an increase in ablation depth in proportion to irradiation energy, and 600 J/cm

Indexed as

ablationcathetercolorectal cancerphotodynamic therapyself‐expandable metallic stent

Identifiers

PMID40060766
PMCPMC11883124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.