Evidence map›Paper›PMID 40060699›Full record

ArticlebioRxiv : the preprint server for biology2025

CCRL2 promotes the interferon-γ signaling response in myeloid neoplasms with erythroid differentiation and mutated

Nour Sabiha Naji, Sergiu Pasca, Theodora Chatzilygeroudi, Pablo Toledano-Sanz, Joseph Rimando, Yashvi Hemani, Brandy Perkins, Xinghan Zeng, Conover Talbot, Bogdan Paun and 22 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Sergiu Pasca
Theodora Chatzilygeroudi
Pablo Toledano-Sanz
Joseph Rimando
Yashvi Hemani
Brandy Perkins
Xinghan Zeng
Conover Talbot
Bogdan Paun
Abdulmuez Abdulmalik
Chen Lossos
Tatianna R Boronina
Ilias Sinanidis
Panagiotis Tsakiroglou
Priyanka Fernandes
Christopher Esteb
Alexander J Ambinder
Robert N Cole
Rena Xian
Ivana Gojo
Suman Paul
Mark J Levis
Amy E DeZern
Leo Luznik
Styliani Karanika
Linda S Resar
Richard J Jones
Frederick Bunz
Lukasz Gondek
Marios Arvanitis
Theodoros KarantanosORCID 0000-0002-6792-8298

Funding

Mechanisms of a therapeutic DNA vaccine targeting Mycobacterium tuberculosis persistersK08AI174959 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Styliani Karanika · 2024 to 2026
$603k
NIAID NIH HHS K08 AI174959
6 · The paper itself

Abstract

Patients with myeloid neoplasms with loss-of-function One Sentence Summary: CCRL2 is overexpressed in AML with loss-of-function

Identifiers

PMID40060699
PMCPMC11888204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.