Evidence map›Paper›PMID 40060643›Full record

ArticlebioRxiv : the preprint server for biology2025

Luminos: open-source software for bidirectional microscopy.

Daniel G Itkis, F Phil Brooks, Hunter C Davis, Raphael Hotter, J David Wong-Campos, Yitong Qi, Bill Z Jia, Madeleine Howell, Marley Xiong, Rebecca Frank Hayward and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel G ItkisDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
F Phil BrooksDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0002-4334-8192
Hunter C DavisDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Raphael HotterDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
J David Wong-CamposDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Yitong QiDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Bill Z JiaDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0002-1138-3217
Madeleine HowellDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Marley XiongDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Rebecca Frank HaywardDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Byung Hun LeeDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Yangdong WangDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Rebecca T PerelmanDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.
Adam E CohenDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0002-8699-2404

Funding

Two-Photon All-Optical Electrophysiology in Behaving MiceRF1NS126043 · NINDS · HARVARD UNIVERSITY · PI COHEN, ADAM EZRA · 2022 to 2022
$2.2M
Chemigenetic voltage indicators for far-red and two-photon imaging in vivoRF1NS133755 · NINDS · BROWN UNIVERSITY · PI ABDELFATTAH, AHMED · 2023 to 2023
$2.2M
Brain-wide correlation of single-cell firing properties to patterns of gene expressionRF1MH117042 · NIMH · HARVARD UNIVERSITY · PI COHEN, ADAM EZRA · 2018 to 2018
$1.2M
NIMH NIH HHS RF1 MH117042NINDS NIH HHS RF1 NS126043NINDS NIH HHS RF1 NS133755
6 · The paper itself

Abstract

Bidirectional microscopy (BDM) combines simultaneous targeted optical perturbation and imaging of biophysical or biochemical signals (e.g. membrane voltage, Ca

Identifiers

PMID40060643
PMCPMC11888241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.