Evidence map›Paper›PMID 40060574›Full record

ArticlebioRxiv : the preprint server for biology2025

Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons.

Jennifer T Stocksdale, Matthew J Leventhal, Stephanie Lam, Yu-Xin Xu, Yang Oliver Wang, Keona Q Wang, Reuben Tomas, Zohreh Faghihmonzavi, Yogi Raghav, Charlene Smith and 21 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Jennifer T Stocksdale
Matthew J Leventhal
Stephanie Lam
Yu-Xin Xu
Yang Oliver Wang
Keona Q Wang
Reuben Tomas
Zohreh Faghihmonzavi
Yogi Raghav
Charlene Smith
Jie Wu
Ricardo Miramontes
Kanchan Sarda
Heather Johnson
Min-Gyoung Shin
Terry Huang
Mikelle Foster
Mariya Barch
Naufa Armani
Chris Paiz
Lindsay Easter
Erse Duderstadt
Vineet Vaibhav
Niveda Sundararaman
Dan P Felsenfeld
Thomas F Vogt
Jennifer Van Eyk
Steve Finkbeiner
Ernest Fraenkel
Leslie M Thompson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's Disease (HD) is caused by a CAG repeat expansion in the gene encoding Huntingtin (HTT

Identifiers

PMID40060574
PMCPMC11888261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.