Evidence map›Paper›PMID 40060570›Full record

ArticlebioRxiv : the preprint server for biology2025

A cell-type specific surveillance complex represses cryptic promoters during differentiation in an adult stem cell lineage.

Neuza R Matias, Lorenzo Gallicchio, Dan Lu, Jongmin J Kim, Julian Perez, Angela M Detweiler, Chenggang Lu, Benjamin Bolival, Margaret T Fuller

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Neuza R MatiasDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-1548-037X
Lorenzo GallicchioDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-5040-0139
Dan LuDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-7492-3954
Jongmin J KimDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-1836-2064
Julian PerezDepartment of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-0022-9967
Angela M DetweilerChan Zuckerberg Biohub, San Francisco, CA 94158, USA.ORCID 0000-0001-7026-5467
Chenggang LuDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Benjamin BolivalDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-5734-5112
Margaret T FullerDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-3804-4987

Funding

Regulation of proliferation and differentiation in the male germ line adult stem cell lineageR35GM136433 · NIGMS · STANFORD UNIVERSITY · PI MARGARET T FULLER · 2020 to 2026
$5.9M
NIGMS NIH HHS R35 GM136433
6 · The paper itself

Abstract

Regulators of chromatin accessibility play key roles in cell fate transitions, triggering onset of novel transcription programs as cells differentiate. In the

Indexed as

chromatin regulationcryptic promotersDrosophilaNuRD complexspermatogenesistranscriptional repression

Identifiers

PMID40060570
PMCPMC11888433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.