Evidence map›Paper›PMID 40060435›Full record

ArticlebioRxiv : the preprint server for biology2025

Persistent dopamine-dependent remodeling of the neural transcriptome in response to pregnancy and postpartum.

Jennifer C Chan, Giuseppina Di Salvo, Ashley M Cunningham, Sohini Dutta, Elizabeth Brindley, Benjamin H Weekley, Ethan Wan, Cindy Zhang, Naguib Mechawar, Gustavo Turecki and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer C ChanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Giuseppina Di SalvoNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ashley M CunninghamNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Sohini DuttaNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Elizabeth BrindleyNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Benjamin H WeekleyNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ethan WanDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Cindy ZhangNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Naguib MechawarDouglas Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada, H4H 1R3.
Gustavo TureckiDouglas Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada, H4H 1R3.
Ian MazeNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

Funding

Molecular studies of neural histone monoaminylation in normal and aberrant brain plasticityR01MH116900 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ian S. Maze · 2019 to 2026
$4.7M
Impact of histone serotonylation domain organization on neurodevelopmentF32MH126534 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHAN, JENNIFER C · 2021 to 2023
$216k
Functional Role for H3 Serotonylation During Critical Periods of Postnatal Brain Development and PlasticityF31NS132558 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CUNNINGHAM, ASHLEY · 2023 to 2024
$70k
Cell-type Specific Roles for H3 Serotonylation During Critical Periods of Postnatal Brain Development and PlasticityF99NS139541 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CUNNINGHAM, ASHLEY · 2024 to 2024
$49k
NIMH NIH HHS F32 MH126534NIMH NIH HHS R01 MH116900NINDS NIH HHS F31 NS132558NINDS NIH HHS F99 NS139541
6 · The paper itself

Abstract

Pregnancy and postpartum experiences represent transformative physiological states that impose lasting demands on the maternal body and brain, resulting in lifelong neural adaptations

Identifiers

PMID40060435
PMCPMC11888212

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.