Evidence map›Paper›PMID 40060406›Full record

ArticlebioRxiv : the preprint server for biology2025

Multiple stressors in the Anthropocene: Urban evolutionary history modifies sensitivity to the toxic effects of crude oil exposure in killifish.

Jane Park, Charles Brown, Chelsea Hess, Madison Armstrong, Fernando Galvez, Andrew Whitehead

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jane ParkDepartment of Environmental Toxicology, University of California Davis, Davis, CA 95616, USA.
Charles BrownDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.
Chelsea HessDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.
Madison ArmstrongDepartment of Evolution and Ecology, University of California Davis, Davis, CA 95616, USA.
Fernando GalvezDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.
Andrew WhiteheadDepartment of Environmental Toxicology, University of California Davis, Davis, CA 95616, USA.

Funding

Mechanisms of reproductive, developmental, and early life stage impacts of marineR01ES021934 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GALVEZ, FERNANDO, GREEN, CHRISTOPHER C · 2012 to 2015
$452k
NIEHS NIH HHS R01 ES021934
6 · The paper itself

Abstract

Persistence of wild species in human-altered environments is difficult, in part because challenges to fitness are complex when multiple environmental changes occur simultaneously, which is common in the Anthropocene. This complexity is difficult to conceptualize because the nature of environmental change is often highly context specific. A mechanism-guided approach may help to shape intuition and predictions about complexity; fitness challenges posed by co-occurring stressors with similar mechanisms of action may be less severe than for those with different mechanisms of action. We approach these considerations within the context of ecotoxicology because this field is built upon a rich mechanistic foundation. We hypothesized that evolved resistance to one class of common toxicants would afford resilience to the fitness impacts of another class of common toxicants that shares mechanisms of toxicity.

Indexed as

cross-resistancecrude oilDeepwater Horizon oil spillecological genomicsevolutionary genomicsFundulus grandisRNA-seqtoxicogenomics

Identifiers

PMID40060406
PMCPMC11888386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.