Evidence map›Paper›PMID 40060347›Full record

ReviewSouth Asian journal of cancer2024

Neoadjuvant Treatment in Rectal Cancer.

Srinath Bhradwaj R, Aditya Sarin, Shyam Aggarwal, Shikha Halder, S Hukku, Taha Mustafa, Vijay Arora, V K Malik, Shivendra Singh, G V Rao and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in South Asian journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Srinath Bhradwaj RDepartment of Medical Oncology, Apollo Cancer Institutes, Hyderabad, Telangana, India.
Aditya SarinDepartment of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India.
Shyam AggarwalDepartment of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India.
Shikha HalderDepartment of Radiation Oncology, Sir Ganga Ram Hospital, New Delhi, India.
S HukkuDepartment of Radiation Oncology, BLK Max Hospital, New Delhi, India.
Taha MustafaDepartment of Colo Rectal Surgery, Sir Ganga Ram Hospital, New Delhi, India.
Vijay AroraDepartment of Laparoscopic Surgery, Sir Ganga Ram Hospital, New Delhi, India.
V K MalikDepartment of Laparoscopic Surgery, Sir Ganga Ram Hospital, New Delhi, India.
Shivendra SinghDepartment of GI Oncosurgery, RGCI, New Delhi, India.
G V RaoDepartment of Gastrointestinal and Minimally Invasive Surgery, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Avinash SaklaniDepartment of Colorectal Surgery, Tata Memorial Hospital, Mumbai, Maharashtra, India.
Rajesh BhojwaniDepartment of Surgical Gastroenterology, Santokba Durlabhji Memorial Hospital, Jaipur, Rajasthan, India.
Saumitra RawatDepartment of Surgical Gastroenterology, SGRH, New Delhi, India.
C SelvasekarClinical Services and Specialist Surgery, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Purvish M ParikhDepartment of Clinical Hematology, Sri Ram Cancer Center, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major advance in rectal cancer was the evidence supporting short-course radiotherapy and long-course chemoradiotherapy. Both have been shown to improve local outcomes. Total neoadjuvant therapy (TNT) is the new kid on the block that provides further benefit of improving local responses as well as reducing systemic relapses, thus increasing overall survival. Details of the four key TNT trials are discussed. They pave the way for nonoperative management for patients who achieve clinical complete responses.

Indexed as

LCCRTNOMSCRTTNT

Identifiers

PMID40060347
PMCPMC11888809

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.