Evidence map›Paper›PMID 40060342›Full record

ReviewSouth Asian journal of cancer2024

Inflammatory Bowel Disease and Colorectal Cancer: An Eternal Fire in a Beautiful Garden.

Venkata Pradeep Babu Koyyala, Chetan Kantharia, Naitica Darooka, Mandhir Kumar, Piyush Ranjan, Shrihari Anikhindi, Naresh Kumar Bansal, Praveen Sharma, Dr V P Bhalla, Manish Kumar and 11 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in South Asian journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in immunology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Venkata Pradeep Babu KoyyalaDepartment of Medical Oncology, Shankara Cancer and Research Institute, Tezpur, Assam, India.ORCID 0000-0002-3968-8354
Chetan KanthariaDepartment of Surgical Gastroenterology, Nanavati Super Specialty Hospital, Mumbai, Maharashtra, India.
Naitica DarookaDepartment of Medicine, KEM Hospital, Mumbai, Maharashtra, India.
Mandhir KumarDepartment of Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Piyush RanjanDepartment of Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Shrihari AnikhindiDepartment of Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Naresh Kumar BansalDepartment of Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Praveen SharmaDepartment of Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Dr V P BhallaDepartment of Surgical Gastroenterology, PSRI Hospital, New Delhi, India.
Manish KumarDepartment of Medical Oncology, Cloud Physician, Bengaluru, Karnataka, India.
Mohit SharmaDepartment of Medical Oncology, Fortis Hospital, Faridabad, Haryana, India.
Deepak AbrolDepartment of Radiation Oncology, American Oncology Institute, Jammu, India.
Peush SahniDepartment of Surgical Gasteroenterology, AIIMS, New Delhi, India.
Ramesh ArdhanariDepartment of Surgical Gastroenterology, Meenakshi Mission Hospital, Madurai, Tamil Nadu, India.
R PradeepDepartment of Surgical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Amitabh YadavDepartment of Surgical Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Suviraj JohnMinimal Access Surgery Department, Sir Ganga Ram Hospital, New Delhi, India.
Saumitra RawatDepartment of Surgical Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India.
Purvish ParikhDepartment of Clinical Hematology, Sri Ram Cancer Center, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, Rajasthan, India.
C SelvasekarDivisional Medical Director, Clinical Services & Specialist Surgery, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Shyam AggarwalDepartment of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, significantly increases the risk of colitis-associated cancer (CAC). Chronic inflammation, a key contributor to carcinogenesis, disrupts immune surveillance, induces deoxyribonucleic acid (DNA) damage, and alters genetic and epigenetic pathways. Molecular pathways such as STAT3, mTOR, and NF-κB drive CAC progression, while unique microbiome alterations-loss of

Indexed as

cytokinehereditary riskimmune deficiencyprecancerous

Identifiers

PMID40060342
PMCPMC11888801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.