Evidence map›Paper›PMID 40060305›Full record

ArticleJournal of biomedical optics2023

Detection of low-frequency oscillations in neonatal piglets with speckle contrast diffuse correlation tomography.

Mehrana Mohtasebi, Daniel Irwin, Dara Singh, Siavash Mazdeyasna, Xuhui Liu, Samaneh Rabienia Haratbar, Faraneh Fathi, Chong Huang, Kathryn E Saatman, Lei Chen and 1 more

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mehrana MohtasebiUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.ORCID 0000-0002-4689-990X
Daniel IrwinUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Dara SinghUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Siavash MazdeyasnaUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Xuhui LiuUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.ORCID 0000-0002-2537-7838
Samaneh Rabienia HaratbarUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Faraneh FathiUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Chong HuangUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.ORCID 0000-0002-5260-9112
Kathryn E SaatmanUniversity of Kentucky, Spinal Cord and Brain Injury Research Center, Department of Physiology, Lexington, Kentucky, United States.
Lei ChenUniversity of Kentucky, Spinal Cord and Brain Injury Research Center, Department of Physiology, Lexington, Kentucky, United States.
Guoqiang YuUniversity of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.

Funding

Noninvasive Noncontact High-Density Optical Imaging of Neonatal Intraventricular HemorrhageR01HD101508 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$2.7M
Time-resolved laser speckle contrast imaging of resting-state functional connectivity in neonatal brainR42MH135825 · NIMH · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2023 to 2025
$2.1M
Development of a Wearable Fluorescence Imaging Device for IntraoperativeIdentification of Brain TumorsR42CA243600 · NCI · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2023 to 2025
$2.0M
Perioperative Diffuse Optical Imaging of Tissue Blood Flow and Oxygenation for Optimization of Mastectomy Skin Flap ViabilityR01EB028792 · NIBIB · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$1.9M
High-density optical tomography of cerebral blood flow and metabolism in small animalsR41NS122722 · NINDS · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2021 to 2022
$688k
Continuous and Longitudinal Monitoring of Cerebral Blood Flow and Metabolism in Freely Moving RodentsR56NS117587 · NINDS · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2020
$613k
A Multiscale Multimodal Diffuse Optical Device for Early Detection of Preclinical Alzheimer’s DiseaseR21HD091118 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2018 to 2019
$568k
Assessment of Muscle Vascular Disease with Diffuse LightR21HL083225 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI YU, GUOQIANG · 2006 to 2007
$436k
Implementing a novel, multimodal technique for monitoring cerebrovascular hemodynamics in mice as a diagnostic and prognostic tool for single and repeated mild TBIR21NS114771 · NINDS · UNIVERSITY OF KENTUCKY · PI SAATMAN, KATHRYN E · 2020 to 2020
$421k
NCI NIH HHS R42 CA243600NHLBI NIH HHS R21 HL083225NIBIB NIH HHS R01 EB028792NICHD NIH HHS R01 HD101508NICHD NIH HHS R21 HD091118NIMH NIH HHS R42 MH135825NINDS NIH HHS R01 AG062480NINDS NIH HHS R21 NS114771NINDS NIH HHS R41 NS122722NINDS NIH HHS R56 NS117587
6 · The paper itself

Abstract

Significance: Low-frequency oscillations (LFOs) ( Aim: We aim to optimize an innovative speckle contrast diffuse correlation tomography (scDCT) system for the detection of LFOs within CBF variations. Approach: The scDCT was optimized to achieve a higher sampling rate and a faster image reconstruction using a moving window 3D reconstruction algorithm with parallel computation. Power spectral density (PSD) analysis was performed to investigate altered LFOs during transient global cerebral ischemia in neonatal piglets. Results: Transient global cerebral ischemia resulted in reductions in both CBF and PSD compared with their baseline values. Conclusions: Spontaneous LFOs, combined with CBF, provide a more comprehensive assay with the potential to clarify pathological mechanisms involved in brain injury. These results support scDCT's inclusion and application in the growing area of LFO analysis and demonstrate its inherent advantage for neurological studies in preclinical and clinical settings, such as neonatal intensive care units.

Indexed as

Animals, NewbornCerebrovascular CirculationAlgorithmsAnimalsBrainBrain IschemiaImage Processing, Computer-AssistedSwineTomographycerebral blood flowlow-frequency oscillationsneonatal pigletneuroimagingspeckle contrast diffuse correlation tomography

Identifiers

PMID40060305
PMCPMC11889336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.