Evidence map›Paper›PMID 40060273›Full record

ArticleBiomicrofluidics2025

Microfluidic tools to model, monitor, and modulate the gut-brain axis.

Hyehyun Kim, Gregory Girardi, Allison Pickle, Testaverde S Kim, Erkin Seker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomicrofluidics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyehyun KimDepartment of Biomedical Engineering, University of California-Davis, Davis, California 95616, USA.ORCID https://orcid.org/0009-0004-3949-7277
Gregory GirardiORCID https://orcid.org/0009-0004-8437-4313
Allison PickleDepartment of Biomedical Engineering, University of California-Davis, Davis, California 95616, USA.ORCID https://orcid.org/0009-0003-4455-1509
Testaverde S KimDepartment of Biomedical Engineering, University of California-Davis, Davis, California 95616, USA.ORCID https://orcid.org/0000-0001-6513-8922
Erkin SekerDepartment of Electrical and Computer Engineering, University of California-Davis, Davis, California 95616, USA.ORCID https://orcid.org/0000-0003-2401-3562

Funding

UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Irva Hertz-Picciotto · 2015 to 2026
$26.0M
Bottom-up, high-throughput prototyping of extracellular vesicle mimetics using cell-free synthetic biologyR01EB034279 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Randy Carney, Cheemeng Tan · 2023 to 2026
$2.5M
A Microfabricated Model of Enteric Epithelium-Neuron Interaction for Studying the Influence of Bacterial MetabolitesR21AT010933 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SEKER, ERKIN · 2020 to 2021
$405k
Neuronal Contribution to the Propagation of Inflammation in the Central Nervous SystemR03NS118156 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SEKER, ERKIN · 2020 to 2021
$216k
NCCIH NIH HHS R21 AT010933NIBIB NIH HHS R01 EB034279NIEHS NIH HHS P30 ES023513NINDS NIH HHS R03 NS118156
6 · The paper itself

Abstract

The gut-brain axis (GBA) connects the gastrointestinal tract and the central nervous system (CNS) via the peripheral nervous system and humoral (e.g., circulatory and lymphatic system) routes. The GBA comprises a sophisticated interaction between various mammalian cells, gut microbiota, and systemic factors. This interaction shapes homeostatic and pathophysiological processes and plays an important role in the etiology of many disorders including neuropsychiatric conditions. However, studying the underlying processes of GBA

Identifiers

PMID40060273
PMCPMC11890156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.