Evidence map›Paper›PMID 40060270›Full record

ReviewJournal of diabetes and metabolic disorders2025

MicroRNAs in diabetes mellitus.

P Shaik Syed Ali, Md Parwez Ahmad, K M Huria Parveen

Abstract readReview
In one paragraph

Review in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

P Shaik Syed AliSchool of Medicine, The Maldives National University, Malé, Maldives.ORCID 0000-0002-5764-665X
Md Parwez AhmadSchool of Medicine, The Maldives National University, Malé, Maldives.
K M Huria ParveenSchool of Medicine, The Maldives National University, Malé, Maldives.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is one of the most common chronic diseases, with a global distribution. Its prevalence is constantly increasing, along with the rising incidence of diabetes-related complications such as diabetic nephropathy, neuropathy, and retinopathy. MicroRNAs are endogenous, non-coding RNAs that regulate gene expression at the post-transcriptional level. Evidence suggests that altered microRNA expression has been implicated in various human disorders, including diabetes mellitus. Dysregulated expression of microRNAs leads to insulin resistance, causing diabetes mellitus and its associated complications. Moreover, other non-coding RNAs, such as long non-coding RNAs and circular RNAs, along with epigenetic factors and altered gut microbiota, contribute to disease development. Because of the stability of non-coding RNAs in circulation, they have the potential to be used as biomarkers for diagnosis and therapeutic implications. Evidence suggests that a myriad of factors are involved; hence, a collective approach involving non-coding RNAs, epigenetic factors, and gut microbiota could provide the best clinical outcomes for diabetes patients. Supplementary Information: The online version contains supplementary material available at 10.1007/s40200-025-01591-y.

Indexed as

Diabetes mellitusDiabetic complicationsMicroRNANon-coding RNA

Identifiers

PMID40060270
PMCPMC11885724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.