ArticleCJC open2025
Acute Electrical Synchronization Achieved With Dynamic Atrioventricular Delays During Biventricular and Left Ventricular MultiPoint Pacing.
Article in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03567096 (Characterization of Acute and Long Term Response to Left Ventricle Only Pacing Combined With MultiPoint Pacing and SyncAV), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Characterization of Acute and Long Term Response to Left Ventricle Only Pacing Combined With MultiPoint Pacing and SyncAV
Who cites it
1 citing paper in PubMed.
- Acute Effects of Fusion Pacing Versus Standard CRT on Myocardial Function in Heart Failure Patients with LBBB.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cardiac resynchronization therapy (CRT) response relies on 2 factors: when and where to pace. These factors may be enhanced by dynamic atrioventricular delays (AVDs) (eg, SyncAV CRT, Abbott Cardiovascular, Abbott Park, IL) and multisite left ventricular (LV) pacing (eg, MultiPoint Pacing [MPP], Abbott). Their individual and combined synchronization contributions have not been evaluated across a comprehensive spectrum of pacing configurations. The objective is to distinguish the acute electrical synchrony achieved by static vs dynamic AVDs, single-site vs multisite LV pacing, and with vs without right ventricular (RV) pacing. Methods: CRT-indicated patients with left bundle branch block (LBBB) and intact atrioventricular (AV) conduction (PR < 250 ms) were enrolled and evaluated during implant. Acute changes in 12-lead electrocardiographic (ECG) QRS duration (QRSd) were evaluated during intrinsic conduction, biventricular pacing (BiV), biventricular MPP, LV-only single-site pacing (LVSS), and LV-only MPP (LVMPP). CRT modes were evaluated with static AVDs and optimized SyncAV AVDs. Results: CRT implant and QRSd evaluation were completed in 85 patients (71% male, 34% ischemic, 179 ms PR). The median intrinsic QRSd of 165 ms was reduced by BiV, MPP, LVSS, and LVMPP without SyncAV to 144 ms (by 14%), 142 ms (16%), 155 ms (8%), and 149 ms (12%), respectively ( Conclusions: MPP combined with SyncAV achieved the narrowest QRSd, in the overall population and in the most patients, by delivering ventricular pacing from all available sites (RV + LV1 + LV2) while timed with dynamic AVDs. Clinical Registration Number: NCT03567096.
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Registered trials
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