Evidence map›Paper›PMID 40060088›Full record

ArticleSouthern African journal of infectious diseases2025

Type and antibiotic susceptibility of bacteria cultured in paediatric acute appendicitis.

Elizabeth Brits, Estie Kruger, Karlize Fivaz, Koot Oosthuizen, Mariska Joubert, Petro-Mari van Pletzen, Ronelle Roux, Tahlita Fourie, Trewhella van Aswegen, Joseph B Sempa and 1 more

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In one paragraph

Article in Southern African journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elizabeth BritsDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0000-0002-6422-9272
Estie KrugerDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0000-8154-4621
Karlize FivazDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0004-1398-1271
Koot OosthuizenDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0004-3221-3227
Mariska JoubertDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0008-6295-2062
Petro-Mari van PletzenDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0007-1891-6067
Ronelle RouxDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0006-0338-913X
Tahlita FourieDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0002-9304-8259
Trewhella van AswegenDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0002-8292-7987
Joseph B SempaDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0000-0003-1062-0417
Susanna le GrangeDepartment of Surgery, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0000-0002-5868-181X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Studying the microbial profile and their antibiotic resistance in paediatric appendicitis is essential for tracking susceptibility, guiding treatment choices and ensuring effectiveness. Understanding variations in therapies can improve outcomes and reduce complications. Despite its importance, limited research has been conducted in South Africa on microbial profiles and antibiotic resistance in paediatric appendicitis. Objectives: To identify bacteria cultured from pus specimens obtained from paediatric patients with acute appendicitis and determine their antibiotic susceptibility. Method: This was a prospective case series of children aged 13 years and younger, who had appendectomies for acute appendicitis. Data were collected via REDCap and analysed using R software. Pus swabs were obtained for microscopy, culture and sensitivity of organisms isolated. Results: The study comprised 20 patients, of whom 12 (60%) were male. Most cases ( Conclusion: Contribution: Regional monitoring and research are useful to adapt protocols and combat increasing antibiotic resistance.

Indexed as

acute appendicitisantibiotic sensitivitymicrobepaediatricresistance

Identifiers

PMID40060088
PMCPMC11886553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.