Evidence map›Paper›PMID 40060073›Full record

ArticleIndian journal of nephrology

Anti-Phospholipase A2 Receptor Antibody Testing to the Rescue.

A S Nath, Siddharth Herur, Gangadhar Taduri, Swarnalatha Guditi, Raja Karthik Kalidindi, Prasanna Murugan, Rahul R Nair, Niranjan Ganesh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A S NathDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Siddharth HerurDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Gangadhar TaduriDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Swarnalatha GuditiDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Raja Karthik KalidindiDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Prasanna MuruganDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Rahul R NairDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Niranjan GaneshDepartment of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serological testing for M-type anti-phospholipase A2 receptor antibodies (antiPLA2R Ab) has abrogated the need for kidney biopsy to diagnose membranous nephropathy in the appropriate clinical setting. We report a case of a 63-year-old hypertensive male who presented with nephrotic syndrome associated with autosomal dominant polycystic kidney disease which was effectively diagnosed with the use of antiPLA2R Ab test. He achieved complete remission upon treatment with Rituximab. Hitherto, all anecdotal case reports of this uncommon association were diagnosed only by kidney biopsy. We highlight the usefulness of PLA2RAb especially in such cases of difficult-to-biopsy kidneys.

Indexed as

Membranous nephropathyNephrotic syndromePLA2RPolycystic kidneysRituximab

Identifiers

PMID40060073
PMCPMC11883324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.