ArticleIndian journal of nephrology
Quality of Life of Children with Idiopathic Nephrotic Syndrome.
Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- A qualitative study on treatment decision-making experiences of primary caregivers of children with difficult-to-treat nephrotic syndrome.International urology and nephrology · 2026Article
- Impact of childhood and parental smoking and substance use on nephrotic syndrome outcomes: a prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Nephrotic Syndrome: Current Management.Indian journal of pediatrics · 2026Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Nephrotic syndrome (NS) is relapsing-remitting illness affecting children and characterized by proteinuria, edema, and hypoalbuminemia. The disease involves the significant formative years of a child's life and profoundly impacts their physical and psychosocial well-being. There is a scarcity of literature exploring the quality of life (QoL) of children with NS and the factors influencing them. The study aimed to discuss the QoL of children with NS and the factors influencing it. Materials and Methods: A systematic search of electronic databases, including PubMed, Google Scholar, and Embase, was carried out from 2004 to August 2023. Nineteen original articles in English language that focused on evaluating the QoL of children with NS were included. Articles in languages other than English, letters, and editorial reviews, studies involving populations other than children, were excluded. Results: Children with NS tend to have a better QoL as compared to those with other chronic diseases (p = <0.001), but it remains lower than that of healthy children (p<0.05). School functioning was the most affected domain. Recurrent relapses, prolonged illness, high steroid dosages, and multiple medications are significant contributors to impaired QoL. Children with steroid-resistant nephrotic syndrome (SRNS) had poorer QoL among the clinical subtypes. Conclusion: Children with NS face various challenges that impact their QoL. Comprehensive care strategies to enhance QoL are the need of the hour.
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