ArticleIndian journal of nephrology
Mass Spectrometric Identification of Urinary Biomarkers of Chronic Kidney Disease: A Proteomic-Related Preliminary Report.
Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Spatial and functional characterization of ER stress proteins links fibroblast plasticity and proliferative processes in human osteoarthritic synovitis.Cell death and differentiation · 2026Article
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5 authors.
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Abstract
Background: Chronic kidney disease (CKD) is a gradual loss of kidney function and has an increased prevalence rate worldwide. Our study was intended to identify potential biomarkers of progression using urine proteomics. Materials and Methods: This preliminary study consisted of 32 patients with stage V CKD. Urine samples were subjected to liquid chromatography-mass spectrometry (LCMS), and the network of protein interaction was analyzed using STRING. Results: A total of 135 proteins were identified, of which 35 were listed as candidates based on their clinical significance. Protein- protein interaction study provides novel insights into the functional constitution of the proteome, selecting urine as a source of biomarkers. Conclusion: The present study observed that the potential markers such as EndoG, HPX, APN, AnxA1, Mic60, LONP1, and HYOU1 correlate with renal damage and its progression to CKD stage V.
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