ArticleNeuropsychiatric disease and treatment2025
Duration Mismatch Negativity in Adults With Autism Spectrum Disorder Versus Healthy Controls.
Article in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Auditory Sensitivity in Autism: A Systematic Review of Mismatch Negativity and Mismatch Field Responses.Autism research : official journal of the International Society for Autism Research · 2026Pooled it
- Sex Differences in Auditory Brainstem Responses of Two Rat Models of Autism: Environmental and Genetic Contributions to Autism-Like Auditory Function.Autism research : official journal of the International Society for Autism Research · 2025Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The mismatch negativity (MMN) reflects automatic cognitive function in response to auditory stimulation. The MMN to duration deviant (d-MMN) amplitude is known to be lower in children with autism spectrum disorder (ASD) than in healthy controls (HCs). Moreover, the d-MMN is known to be a trait maker of schizophrenia because it is unaffected by the duration of illness. This study aimed to identify robust tools to distinguish adults with ASD from HCs by measuring the d-MMN. Methods: Fifteen adults with ASD (age range, 20-40 years) and 20 HCs were compared. After excluding patients with a low intelligence quotient, those using central nervous system stimulants, and those with excessive alcohol consumption, we conducted an auditory oddball task to measure the d-MMN. Results: Compared with HCs, the patients with ASD showed significantly shorter d-MMN latencies for Fz and Cz. Conclusion: The present findings suggest that the automatic cognitive function indicated by MMN amplitude might be improved by growth. Alternatively, the hypersensitivity indicated by d-MMN latencies suggests that it could persist into adulthood. Significance: The d-MMN latency was shortened in patients with ASD compared with HCs. We believe that this is the first report to reveal that hypersensitivity in ASD as reflected by a shortened d-MMN latency should be maintained, even in adults.
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