Evidence map›Paper›PMID 40059961›Full record

ArticleJournal of experimental orthopaedics2025

Patients treated for infection following ACL reconstruction with graft removal have poorer outcomes than those treated with graft retention: A systematic review.

Daniel C Lewis, Natalya E McNamara, Erin M Tabish, Joseph T Featherall, Hillary W Rawson, Gregoire Micicoi, Daniel J Song, Justin J Ernat

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. AcuteThe Journal of international medical research · 2026
    Article
  2. Infection Following ACL Reconstruction: From Prevention to Treatment.The archives of bone and joint surgery · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel C LewisDepartment of Orthopedic Surgery University of Utah Health Salt Lake City Utah USA.ORCID 0000-0002-9424-3809
Natalya E McNamaraDepartment of Orthopedic Surgery University of Utah Health Salt Lake City Utah USA.ORCID 0000-0002-3208-462X
Erin M TabishSchool of Medicine University of Utah Salt Lake City Utah USA.ORCID 0000-0002-9303-6269
Joseph T FeatherallDepartment of Orthopedic Surgery University of Utah Health Salt Lake City Utah USA.ORCID 0000-0002-2634-9484
Hillary W RawsonDepartment of Orthopedic Surgery University of Utah Health Salt Lake City Utah USA.ORCID 0009-0000-4497-6820
Gregoire MicicoiUnité de Recherche Clinique Côte d'Azur (UR2CA) Université Côte d'Azur Nice France.ORCID 0000-0001-8279-880X
Daniel J SongSports Medicine Division Evans Army Community Hospital Fort Carson Colorado USA.ORCID 0000-0002-2214-5986
Justin J ErnatDepartment of Orthopedic Surgery University of Utah Health Salt Lake City Utah USA.ORCID 0000-0003-2306-7745

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to evaluate patient outcomes following anterior cruciate ligament reconstruction (ACLR) complicated by septic arthritis treated with graft retention versus graft removal protocols. Secondarily, this study aimed to evaluate surgical, demographic and microbial surgical indications for graft retention versus graft removal. We hypothesised that patients who underwent graft removal would have worse outcomes and that patients with septic arthritis caused by more virulent organisms, such as methicillin-resistant Methods: A systematic review and meta-analysis of literature in the PubMed and Ovid databases regarding the treatment of septic arthritis following ACLR reporting graft retention versus graft removal was conducted. The included studies were published in English, in peer-reviewed journals, with an average minimum follow-up of 1 year, and reported on arthroscopic ACLR, surgical management of infection, graft retention versus graft removal during treatment and outcome measures. Patient demographic, surgical and outcome data were analysed. Results: Twenty-four studies reporting on 307 patients were included for analysis. Patients who underwent allograft ACLR ( Conclusions: Septic arthritis following ACLR is a devastating complication. Both graft retention and graft removal protocols have been reported and are viable options. Patients treated with graft removal had poorer outcome measures. Septic arthritis caused by Clinical Relevance: Septic arthritis following ACLR remains an uncommon, but difficult problem. There is minimal literature guiding graft retention versus graft removal treatment protocols. Level of Evidence: Level IV systematic review of lower-level studies.

Indexed as

ACL reconstructiongraft removalgraft retentioninfectionseptic arthritissystematic review

Identifiers

PMID40059961
PMCPMC11885414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.