ArticleJournal of inflammation research2025
Association Between Uric Acid to High-Density Lipoprotein Cholesterol Ratio and Abdominal Aortic Aneurysm: A Single-Center Retrospective Study.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- The uric acid to high density lipoprotein cholesterol ratio as a new indicator for predicting coronary slow flow phenomenon.BMC cardiovascular disorders · 2025Article
- The ratio of serum uric acid to high-density lipoprotein cholesterol as a predictor for frailty prevalence and mortality in the elderly U.S. adults.Lipids in health and disease · 2025Article
- Diagnostic value of platelet to high-density lipoprotein cholesterol ratio in abdominal aortic aneurysms.Frontiers in cardiovascular medicine · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Uric acid (UA) to high-density lipoprotein cholesterol (HDL-C) ratio (UHR) has been recognized as a novel biomarker for evaluating inflammatory and anti-inflammatory interaction. However, it is not known whether UHR is related to abdominal aortic aneurysm (AAA). The current research aims to explore the potential role of UHR in predicting AAA. Methods: In this study, 303 AAA patients and 408 normal subjects were retrospectively analyzed. The relationship between UHR and AAA was evaluated using Logistic regression models. Receiver operating characteristic (ROC) curves and restricted cubic spline (RCS) analysis were employed to elucidate the detailed association between UHR and AAA. Results: UHR value in the AAA group was significantly higher than that in the normal group, and UHA was an independent risk factor for AAA. After adjusting for covariates, each 1-unit increase in UHR was associated with a 12% rise in AAA risk (OR: 1.12, 95% CI: 1.03, 1.21). ROC value of UHR was 0.847 (95% CI, 0.811~0.887, P < 0.05), and the optimal critical value of UHR was 17.2%. The incidence of AAA in the UHR≥17.2% group was significantly higher than that in the UHR < 17.2% group. RCS curves revealed a significant nonlinear relationship between UHR and AAA events (p-value < 0.001, p-nonlinear = 0.002). Conclusion: This study demonstrates that UHR levels are significantly linked to increased AAA risk, which can be widely used as an indicator for dynamic screening of AAA.
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