Evidence map›Paper›PMID 40059879›Full record

ArticleOpen life sciences2025

Calcium-sensing receptors promoted Homer1 expression and osteogenic differentiation in bone marrow mesenchymal stem cells.

Kainan Liu, Tianjie Xu, Jiaxin Fan, Yueyuan Li, Xiaoling Guo, Hui Zhang, Qian Wang

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kainan LiuSchool of Basic Medical Sciences, North China University of Science and Technology, Bohai Road, Caofeidian District, Tangshan, Hebei, 063210, China.
Tianjie XuSchool of Basic Medical Sciences, North China University of Science and Technology, Bohai Road, Caofeidian District, Tangshan, Hebei, 063210, China.
Jiaxin FanSchool of Basic Medical Sciences, North China University of Science and Technology, Bohai Road, Caofeidian District, Tangshan, Hebei, 063210, China.
Yueyuan LiSchool of Basic Medical Sciences, North China University of Science and Technology, Bohai Road, Caofeidian District, Tangshan, Hebei, 063210, China.
Xiaoling GuoSchool of Basic Medical Sciences, North China University of Science and Technology, Bohai Road, Caofeidian District, Tangshan, Hebei, 063210, China.
Hui ZhangDepartment of Joint Surgery, The Second Hospital of Tangshan, Tangshan, Hebei, 063000, China.
Qian WangSchool of Basic Medical Sciences, North China University of Science and Technology, Bohai Road, Caofeidian District, Tangshan, Hebei, 063210, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homer1 interacts with calcium-sensing receptors (CaSRs) in osteoblasts (OBs), with both CaSR and Homer1 playing essential roles in AKT phosphorylation. This study investigated the impact of CaSR on Homer1 expression during the differentiation of rat bone marrow mesenchymal stem cells (BMSCs) at morphological, imaging, and molecular levels, both

Indexed as

bone marrow mesenchymal stem cellscalcium-sensing receptorosteogenic differentiation.

Identifiers

PMID40059879
PMCPMC11889507

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.