Evidence map›Paper›PMID 40059854›Full record

ReviewNeurourology and urodynamics2025

Can We Improve Our Routine Urological Assessment to Exclude Neurogenic Causes for Lower Urinary Tract Dysfunction? ICI-RS 2024.

Marcus J Drake, Salvador Arlandis, Marcio A Averbeck, Enrico Finazzi Agrò, Claire Hentzen, Giovanni Mosiello, Jalesh Panicker, Matthew Smith, Katie Webb

Abstract readReview
In one paragraph

Review in Neurourology and urodynamics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcus J DrakeDepartment of Surgery and Cancer, Imperial College, London, UK.ORCID http://orcid.org/0000-0002-6230-2552
Salvador ArlandisDepartment of Urology, La Fe University and Polytechnic Hospital, Valencia, Spain.ORCID http://orcid.org/0000-0002-1224-9423
Marcio A AverbeckDepartment of Urology, Moinhos de Vento Hospital, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-8127-7153
Enrico Finazzi AgròDepartment of Surgical Sciences, University of Rome "Tor Vergata", Rome, Italy.ORCID http://orcid.org/0000-0002-0308-8824
Claire HentzenGRC 01, GREEN Group of clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Sorbonne University, Paris, France.ORCID http://orcid.org/0000-0002-9223-4925
Giovanni MosielloDivision of Neuro-Urology, Bambino Gesù Children Hospital and Research Institute, Rome, Italy.ORCID http://orcid.org/0000-0002-9626-9519
Jalesh PanickerDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.ORCID http://orcid.org/0000-0001-5190-3259
Matthew SmithDepartment of Neurology, North Bristol NHS Trust, Bristol, UK.ORCID http://orcid.org/0000-0002-4685-375X
Katie WebbDepartment of Physiotherapy, St Mary's Hospital, Imperial College Healthcare Trust, London, UK.ORCID http://orcid.org/0009-0005-1986-4524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAfter presentation with urinary symptoms, an underlying neurological mechanism sometimes emerges subsequently. Increased awareness may bring earlier diagnosis, improving prognosis and outcomes.

methodsA 2024 International Consultation on Incontinence Research Society think-tank considered the clinical pathway for identification of an undiagnosed neurological or autonomic contribution precipitating urinary symptoms, and the implications for prognosis.

resultsAlongside adult-onset neurogenic conditions, potential for missed diagnosis includes congenital and pediatric-acquired neurogenic conditions, which may become symptomatic during a growth spurt due to spinal cord tethering. Detailed assessment is needed, also considering bowel and sexual dysfunction, with timely referral to neurology to reduce preventable progression of disease. In neurological assessment, control of micturition is often poorly characterized compared with other aspects of spinal cord function and the cranial nerves. Screening tools may be used to identify people who have increased likelihood of particular conditions, but currently available tools are either single-system or population specific. In addition to the general pelvic examination, the assessment of sacral reflexes and pelvic sensations can suggest a neurological mechanism, though the sensitivity and specificity of the neuro-urological examination is unknown. Including the results of the neuro-perineal examination in the urodynamic report may improve the interpretation of the results and potentially support a neurological aetiology.

conclusionFuture research should consider the value of neuro-urological examination in diagnosis of occult neurological disease, the development of an occult neurology screening tool/risk scoring based on pelvic organ symptoms, and appropriateness of non-neurologist practitioners requesting neurological investigations such as MRI scanning. CLINICAL

trial registrationDoes not apply.

Indexed as

Lower Urinary Tract SymptomsUrinary Bladder, NeurogenicHumansNeurologic ExaminationUrodynamicsautonomicLUTSneuro‐urologySpina bifidaurodynamics

Identifiers

PMID40059854
PMCPMC11920931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.