Evidence map›Paper›PMID 40059341›Full record

ArticleMolecular pharmaceutics2025

ImmunoPET Imaging of Trop2 Expression in Bladder Cancer Using [

Wenpeng Huang, Tianyao Wang, Fangfang Chao, Qi Yang, Jason C Mixdorf, Liming Li, Jonathan W Engle, Yu Fan, Lei Kang, Weibo Cai

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Noninvasive ImmunoPET imaging of PD-L1 expression in non-small cell lung cancer and bladder cancer using [Colloids and surfaces. A, Physicochemical and engineering aspects · 2025
    Article
  7. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  8. Article
  9. Article
  10. [American journal of nuclear medicine and molecular imaging · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenpeng HuangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Tianyao WangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Fangfang ChaoDepartment of Nuclear Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, China.
Qi YangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Jason C MixdorfDepartments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, Wisconsin 53705, United States.
Liming LiDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, China.
Jonathan W EngleDepartments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0002-3399-7228
Yu FanDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Lei KangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.ORCID 0000-0001-8729-4547
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0003-4641-0833

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

Trop2 exhibits significantly elevated expression in numerous solid malignancies, playing a crucial role in tumor advancement, whereas its presence in healthy tissues is minimal. In this study, we investigated Trop2 expression in bladder cancer models using [

Indexed as

Antigens, NeoplasmCell Adhesion MoleculesCopper RadioisotopesPositron-Emission TomographyUrinary Bladder NeoplasmsAnimalsCell Line, TumorFemaleHeterocyclic Compounds, 1-RingHumansMiceRadiopharmaceuticalsTissue Distribution1,4,7-triazacyclononane-N,N',N''-triacetic acidAntigens, NeoplasmCell Adhesion MoleculesCopper RadioisotopesHeterocyclic Compounds, 1-RingRadiopharmaceuticalsTACSTD2 protein, humanantibody-drug conjugatebladder cancerCu-64ImmunoPETradioactive tracerTrop2

Identifiers

PMID40059341
PMCPMC11978314

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.