Evidence map›Paper›PMID 40059294›Full record

ReviewThe FEBS journal2025

When the host senses the microbiota's metabolism - the interplay between food and microbiota in C. elegans.

José Eduardo Gomes

Abstract readReview
In one paragraph

Review in The FEBS journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

José Eduardo GomesARNA - Nucleic Acids: Natural and Artificial Regulations, Inserm U1212, CNRS UMR 5320 and Université de Bordeaux, Institut Européen de Chimie et Biologie, Pessac, France.ORCID 0000-0001-7264-9448

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbiota plays a major role in metazoan physiology, particularly in the intestinal tract. Nonetheless, its extreme complexity hinders functional studies. Taking advantage of the Caenorhabditis elegans and Escherichia coli model systems, Feng et al. report the physiological effect of purine biosynthesis deficiencies in E. coli-the microbiota in this experimental system-on C. elegans. Mutant E. coli bacteria, particularly those harboring mutations in the purE gene, trigger a stress response in C. elegans. The E. coli purE mutant is defective for the enzyme N

Indexed as

Caenorhabditis elegansEscherichia coliGastrointestinal MicrobiomeMicrobiotaAnimalsbacteriaC. elegansE. colimetabolismmicrobiotaN5‐CAIRnematodespurines

Identifiers

PMID40059294
PMCPMC12138157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.