ArticleBMC oral health2025
Evaluation of the effects of traditional irrigation solutions and etidronic acid on the bond strength of endodontic sealers.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Effect of Dual Rinse HEDP on the push-out bond strength of AH Plus and AH Plus Bioceramic sealers: an in vitro study.BMC oral health · 2026Article
- Role of root canal sealers and dentin surface pretreatment on pull-out strength of customized resilient ceramic posts-and-cores.BMC oral health · 2025Article
- Effect of EDTA, NaOCl, and HEDP-based irrigants on the mechanical properties of heat treated NiTi endodontic instruments.BDJ open · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndodontic sealers are expected to provide a favorable adhesion for a successful seal. This study aimed to evaluate the effect of ethylenediaminetetraacetic acid (EDTA) and Hydroxyethylidene Diphosphonic acid (HEDP) on bond strength of AH Plus and EndoSequence BC HiFlow sealers to root canal walls.
methodsThis study utilized 144 mandibular human premolars. Root canals were shaped using ProTaper Next system. Teeth were divided into 4 groups of 36 according to final irrigation: Group 1: NaOCl, EDTA; Group 2: NaOCl, HEDP (mixed with distilled water); Group 3: HEDP (mixed with NaOCl); Group 4: NaOCl only. Teeth were then divided into 2 subgroups (n = 18) and filled by AH Plus or BC Sealer HiFlow using warm vertical compaction. Teeth were kept at 37 °C with 100% humidity for 7 days. Using the IsoMet device, horizontal sections with a thickness of approximately 1 mm were taken from each sample from the apical, middle and coronal third of the root. Bond strength was tested using an Instron universal testing device at a constant speed of 1 mm/min until failure. Statistical analysis was performed using Shapiro-Wilk normality test, one-way analysis of variance and Three-Way ANOVA for intergroup comparisons.
resultsStatistically significant differences were observed between all groups (p = 0,0001). Push-out averages of NaOCl, EDTA group were significantly higher than NaOCl, HEDP; HEDP (NaOCl) and NaOCl groups (p = 0,0001). Push-out averages of NaOCl group were significantly lower than NaOCl, HEDP and HEDP (NaOCl) groups (p = 0,0001). No significant difference was observed between AH Plus and BC Sealer HiFlow (p = 0,883). Push out averages of the apical region were significantly higher than others and those of middle region were significantly higher than coronal (p = 0,0001). Cohesive failure was prevalent in NaOCl, EDTA, NaOCl, HEDP and HEDP (NaOCl) groups and mixed failure was prevalent in NaOCl group.
conclusionsIrrigation using chelating agents such as EDTA and HEDP mixed with NaOCl gave higher adhesion compared to teeth where only NaOCl was used. EDTA and HEDP mixed with NaOCl can be advocated both for resin based and calcium silicate based sealers.
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