Evidence map›Paper›PMID 40058292›Full record

ArticleCell calcium2025

Mitochondrial Ca

Tam Nguyen, Zhihong Lin, Nirav Dhanesha, Rakesh B Patel, Mallorie Lane, Grant C Walters, Leonid P Shutov, Stefan Strack, Anil K Chauhan, Yuriy M Usachev

Abstract read
In one paragraph

Article in Cell calcium, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Mitochondrial CaBiomolecules · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tam NguyenDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Zhihong LinDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Nirav DhaneshaDepartment of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Rakesh B PatelDepartment of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Mallorie LaneDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Grant C WaltersDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Leonid P ShutovDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Stefan StrackDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Anil K ChauhanDepartment of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Yuriy M UsachevDepartment of Neuroscience and Pharmacology and Iowa Neuroscience Institute, University of Iowa College of Medicine, Iowa City, IA 52242, USA. Electronic address: yuriy-usachev@uiowa.edu.

Funding

Predoctoral Training in the Pharmacological SciencesT32GM067795 · NIGMS · UNIVERSITY OF IOWA · PI STRACK, STEFAN · 2004 to 2021
$3.4M
The Role of the Complement System in Spinal Mechanisms of Chronic PainR01NS113189 · NINDS · UNIVERSITY OF IOWA · PI USACHEV, YURIY M · 2019 to 2023
$2.2M
The mitochondrial Ca2+ uniporter in the regulation of neural activity and susceptibility to seizuresR01NS125884 · NINDS · UNIVERSITY OF IOWA · PI Yuriy M Usachev · 2022 to 2026
$2.2M
Novel Circuits and Mechanisms of Descending Pain ModulationR01NS127428 · NINDS · UNIVERSITY OF IOWA · PI ALEXANDER G BASSUK, Yuriy M Usachev · 2023 to 2026
$2.1M
NIGMS NIH HHS T32 GM067795NINDS NIH HHS R01 NS113189NINDS NIH HHS R01 NS125884NINDS NIH HHS R01 NS127428
6 · The paper itself

Abstract

Mitochondrial Ca

Indexed as

CalciumCalcium ChannelsIschemic StrokeNeuronsAnimalsInfarction, Middle Cerebral ArteryMaleMembrane Potential, MitochondrialMiceMice, Inbred C57BLMice, KnockoutMitochondriaCalciumCalcium Channelsmitochondrial calcium uniportercalciumexcitotoxicityIschemiaMCAOMCUMCUbMitochondriastroke

Identifiers

PMID40058292
PMCPMC12094165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.