Evidence map›Paper›PMID 40057956›Full record

ArticleCell reports2025

An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.

Huiyuan Zhang, Asaf Madi, Nir Yosef, Norio Chihara, Amit Awasthi, Caroline Pot, Conner Lambden, Amitabh Srivastava, Patrick R Burkett, Jackson Nyman and 15 more

Abstract readPublished Erratum
In one paragraph

Article in Cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Huiyuan Zhang
Asaf Madi
Nir Yosef
Norio Chihara
Amit Awasthi
Caroline Pot
Conner Lambden
Amitabh Srivastava
Patrick R Burkett
Jackson Nyman
Elena Christian
Yasaman Etminan
Annika Lee
Helene Stroh
Junrong Xia
Katarzyna Karwacz
Pratiksha I Thakore
Nandini Acharya
Alexandra Schnell
Chao Wang
Lionel Apetoh
Orit Rozenblatt-Rosen
Ana C Anderson
Aviv Regev
Vijay K Kuchroo

Funding

Role of Negative Costimulation in Regulation of AutoimmunityP01AI039671 · NIAID · YALE UNIVERSITY · PI David A. Hafler · 1996 to 2026
$51.7M
Transgenic / Knock-out mouse coreP01AI073748 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BEHAR, SAMUEL M · 2008 to 2019
$17.1M
Translational Core (Expression Core)P01AI129880 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROTHSTEIN, DAVID M · 2018 to 2022
$9.4M
Role of Tim-3:Bat-3 pathway in inducing tolerogenic DCs and peripheral toleranceR01AI144166 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI VIJAY K. KUCHROO · 2020 to 2026
$3.2M
Role of Tim-l in B Cells in regulating autoimmunity in the CNSR01AI185514 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI VIJAY K. KUCHROO · 2024 to 2026
$1.9M
NIAID NIH HHS P01 AI039671NIAID NIH HHS P01 AI073748NIAID NIH HHS P01 AI129880NIAID NIH HHS R01 AI144166NIAID NIH HHS R01 AI185514
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40057956
PMCPMC12121354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.