Evidence map›Paper›PMID 40057926›Full record

ArticleUpdates in surgery2025

The impact of postoperative recurrent postoperative ileus on the prognosis of colorectal cancer: a propensity score matched study.

Run Xie, Cuiping Qiu, Runsheng Lai, Zhipeng Que, Shuangming Lin, Dongbo Xu

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Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Run Xie *Department of Colorectal Surgery and Gastroenterology, Longyan First Affiliated Hospital of Fujian Medical University, 105 Jiuyi North Road, Longyan, 364000, Fujian, China.
Cuiping Qiu *Department of Colorectal Surgery and Gastroenterology, Longyan First Affiliated Hospital of Fujian Medical University, 105 Jiuyi North Road, Longyan, 364000, Fujian, China.
Runsheng LaiDepartment of Colorectal Surgery and Gastroenterology, Longyan First Affiliated Hospital of Fujian Medical University, 105 Jiuyi North Road, Longyan, 364000, Fujian, China.
Zhipeng QueDepartment of Colorectal Surgery and Gastroenterology, Longyan First Affiliated Hospital of Fujian Medical University, 105 Jiuyi North Road, Longyan, 364000, Fujian, China.
Shuangming LinDepartment of Colorectal Surgery and Gastroenterology, Longyan First Affiliated Hospital of Fujian Medical University, 105 Jiuyi North Road, Longyan, 364000, Fujian, China.
Dongbo XuDepartment of Colorectal Surgery and Gastroenterology, Longyan First Affiliated Hospital of Fujian Medical University, 105 Jiuyi North Road, Longyan, 364000, Fujian, China. xdb2292388@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the correlation between recurrent postoperative ileus (RPOI) and clinical prognosis in patients with colorectal cancer after radical surgery. A retrospective analysis of 682 stage I-III colorectal cancer patients undergoing surgery at Longyan First Hospital, Fujian Medical University (January 2016-December 2018), identified 50 patients (7.3%) with RPOI and 632 (92.7%) without. The primary endpoints were 3-year recurrence-free survival (RFS) and 3-year overall survival (OS). RFS and OS were compared using the Kaplan-Meier method. A Cox regression model was leveraged to appraise independent prognostic factors. The 3-year RFS rate in the RPOI group was 70.3%, significantly lower than that in the non-RPOI group (82.2%, P = 0.032); the 3-year OS rate in the RPOI group was 71.2%, also significantly lower than that in the non-RPOI group (90.7%, P = 0.004). After propensity score matching (PSM), the results remained unchanged. Univariate regression analysis indicated that lymphovascular invasion, nerve invasion, pT stage, pN stage, pTNM stage, preoperative serum carcinoembryonic antigen levels, RPOI, and serum albumin levels on the first postoperative day (POD 1) were associated with RFS in colorectal cancer patients (all P < 0.05). Multivariate analysis confirmed RPOI (HR = 2.240, 95% CI: 1.104-4.544, P = 0.025) as an independent negative prognostic factor for RFS. Patients who develop RPOI after radical colorectal cancer surgery experience longer intervals before their first postoperative chemotherapy, longer hospital stays, and poorer RFS and OS.

Indexed as

Colorectal NeoplasmsIleusPostoperative ComplicationsAgedFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisPropensity ScoreRetrospective StudiesSurvival RateColorectal cancerPrognosisPropensity matchingRecurrent postoperative ileusSurgery

Identifiers

PMID40057926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.