Evidence map›Paper›PMID 40057847›Full record

ReviewJournal of natural products2025

Connecting the Practice of Modern Qualitative and Quantitative NMR Analysis with Its Theoretical Foundation.

Lucy Botros, Yang Liu, Charlotte Corbett, Dan Sørensen, Christina Szabo, Anton Bzhelyansky, Matthias Niemitz, Petrus Korhonen, Guido F Pauli, Patrick Giraudeau and 1 more

Abstract readReview
In one paragraph

Review in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. QuantitativeMolecules (Basel, Switzerland) · 2026
    Review
  2. Article
  3. NMR-Based Quantification of Collagen Content in Protein Hydrolysates.Journal of agricultural and food chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lucy BotrosSTEMCELL Technologies, Vancouver, British Columbia, V6A 1B6, Canada.
Yang LiuScience, General Chapters, U.S. Pharmacopeial Convention, Rockville, Maryland 20852, United States.ORCID 0000-0002-8064-7108
Charlotte CorbettDrug Enforcement Administration, Dulles, Virginia 20166, United States.
Dan SørensenRegulatory Operations and Enforcement Branch, Health Canada, Ottawa, Ontario, K1A 0K9, Canada.ORCID 0000-0001-5941-4038
Christina SzaboBaxter Healthcare, Round Lake, Illinois 60073, United States.
Anton BzhelyanskyDietary Supplements and Herbal Medicines, U.S. Pharmacopeial Convention, Rockville, Maryland 20852, United States.ORCID 0000-0001-6184-9284
Matthias NiemitzNMR Solutions, 70110 Kuopio, Finland.ORCID 0000-0002-5452-5203
Petrus KorhonenNMR Solutions, 70110 Kuopio, Finland.
Guido F PauliPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois College of Pharmacy, Chicago, Illinois 60612, United States.ORCID 0000-0003-1022-4326
Patrick GiraudeauNantes Université, CNRS, CEISAM UMR 6230, F-44000 Nantes, France.
G Joseph RayPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois College of Pharmacy, Chicago, Illinois 60612, United States.

Funding

Van Breemen: Project 3; Botanical Dietary Supplements - Metabolism and Safety in Women (Van Breemen)P50AT000155 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 1999 to 2019
$30.4M
Center for Natural Product Technologies at UIC (CeNAPT)U41AT008706 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 2015 to 2019
$1.5M
NCCIH NIH HHS P50 AT000155NCCIH NIH HHS U41 AT008706
6 · The paper itself

Abstract

This Perspective seeks to reconnect the current practice of nuclear magnetic resonance (NMR) spectroscopy in chemical structure and quantitative (qNMR) analysis with its roots in classical physics and quantum mechanics (QM). Rationales for this approach are derived from various angles, including focused reviews of the key parameters of the nuclear resonance phenomenon, the structural information richness of NMR spectra, and significant progress in both computational and spectrometer hardware. This provides collective reasoning for the reintegration of computational quantum mechanical spectral analysis (QMSA) into the contemporary practice of NMR spectral interpretation. Retethering operator-dependent visual

Indexed as

Magnetic Resonance SpectroscopyMolecular StructureNuclear Magnetic Resonance, BiomolecularQuantum Theory1H NMR analysisNMR terminologyquantitative NMRquantum mechanical spectral analysis

Identifiers

PMID40057847
PMCPMC11959607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.