Evidence map›Paper›PMID 40057812›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2025

Proceedings of the Alzheimer's Diagnosis in Older Adults With Chronic Conditions Network Inaugural Annual Conference.

Michelle M Mielke, Nicole R Fowler, Heather E Whitson, Heidi D Klepin, Antoine R Trammell, Ambar Kulshreshtha, Kyra S O'Brien, Margaret Manchester, Marcel E Salive, Jeff Williamson

Abstract readConference Proceedings
PubMed Full text at PMC Publisher
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Evaluation of plasma p-tau217 for detecting amyloid pathology in a heterogeneous community-based cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michelle M MielkeDepartment of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0001-7177-1185
Nicole R FowlerDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Heather E WhitsonDepartments of Opthalmology, Medicine, and Neurology, Duke School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-8417-4846
Heidi D KlepinSection on Hematology and Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.ORCID 0000-0002-6262-1123
Antoine R TrammellDepartment of Medicine and Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ambar KulshreshthaDepartment of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.
Kyra S O'BrienDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Margaret ManchesterSchool of Public Health, Georgia State University, Atlanta, Georgia, USA.
Marcel E SaliveNational Institute on Aging, Bethesda, Maryland, USA.
Jeff WilliamsonSection on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.

Funding

Wake Forest University School of Medicine Alzheimer's Disease Research CenterP30AG072947 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUZANNE CRAFT · 2021 to 2026
$24.3M
Research Education Component CoreP30AG072958 · NIA · DUKE UNIVERSITY · PI Maria Marquine · 2021 to 2026
$24.1M
Alzheimer Diagnosis in older Adults with Chronic Conditions ADACC NetworkU24AG082930 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicole R. Fowler, Thomas K Karikari · 2023 to 2026
$7.3M
NIA NIH HHS P30 AG072947NIA NIH HHS P30 AG072958NIA NIH HHS U24 AG082930NIA NIH HHS U24AG082930NIH HHSU.S. Department of Health and Human Services
6 · The paper itself

Abstract

The Alzheimer's Disease in Older Adults with Chronic Conditions (ADACC) Network is funded by the National Institute on Aging as a U24 cooperative agreement. ADACC is an inclusive, multidisciplinary group across multiple institutions that is charged with the task of developing evidence-based strategies for the use and implementation of Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) biomarkers among older adults with cognitive impairment and multiple chronic conditions (MCCs). This report summarizes highlights of the First Annual Symposium of ADACC, which was held in Winston-Salem, North Carolina, in April 2024. An overview of the ADACC Network and goals were initially described, followed by a state of the science integrating biomarkers, AD/ADRD, and MCCs. Multiple presentations on a variety of topics were featured, including the significance of MCCs in AD/ADRD, the effects of MCCs on Alzheimer's blood-based biomarkers, the incorporation of AD/ADRD biomarkers into cancer care, the need to address racial and biomarker disparities, clinician and patient perspectives on plasma AD/ADRD biomarker testing, and ethical considerations. ADACC emphasized the importance of supporting emerging researchers and fostering a collaborative environment.

Indexed as

Alzheimer DiseaseMultiple Chronic ConditionsBiomarkersChronic DiseaseCognitive DysfunctionHumansNational Institute on Aging (U.S.)United StatesBiomarkersBiomarkersComorbidityDementiaDiagnosis

Identifiers

PMID40057812
PMCPMC12066001

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.