ArticleEuropean journal of clinical nutrition2025
Updated nutrient profiling system underlying nutri-score (Uns-Nps) and colorectal cancer risk.
Article in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundGlobally, poor diet is responsible for about 8 million deaths for non-communicable diseases, including cancers, in 2019. One strategy to promote healthier choices by informing consumers about food nutritional properties is the Front-Of-Pack Nutrition Labels, like Nutri-Score. Our study investigated the association between the updated Nutrient Profiling System (uNS-NPS), underlying Nutri-Score, and Colorectal Cancer (CRC) risk.
methodsData from two hospital-based case-control studies were used. Cases were CRC patients, while controls were individuals admitted for acute non-neoplastic conditions. Dietary habits were assessed via a validated food frequency questionnaire. The uNS-NPS dietary index (uNS-NPS-DI) was derived as the weighted average of the uNS-NPS scores of every food/beverage, for the energy intake provided by that food/beverage. Logistic regression models were employed to estimate the odds ratios (OR) and the corresponding 95% confidence intervals (CI) for the association between uNS-NPS-DI (as continuous and as categorical variable, based on quartiles of its distribution among controls) and CRC risk, adjusting for known risk factors.
findingsA total of 2419 cases and 4723 controls were analysed. uNS-NPS-DI distribution (median 6.14, IQR: 5.17-7.15) was similar between cases and controls. Individuals in the highest quartile of uNS-NPS-DI (i.e. with the lowest nutritional quality of their diet) compared to those in the lowest showed a higher CRC risk (OR 1.17, 95% CI: 1.01-1.36).
conclusionsA diet with low nutritional quality as measured by the uNS-NPS was modestly associated with increased CRC risk.
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