Evidence map›Paper›PMID 40057626›Full record

ArticleFood and environmental virology2025

Navigating Uncertainties in RT-qPCR and Infectivity Assessment of Norovirus.

Razieh Sadat Mirmahdi, Samantha L Dicker, Nuradeen Garba Yusuf, Naim Montazeri

Abstract readEvaluation Study
In one paragraph

Article in Food and environmental virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Razieh Sadat MirmahdiFood Science and Human Nutrition Department, University of Florida, 572 Newell Drive, Gainesville, FL, 32611, USA.
Samantha L DickerFood Science and Human Nutrition Department, University of Florida, 572 Newell Drive, Gainesville, FL, 32611, USA.
Nuradeen Garba YusufFood Science and Human Nutrition Department, University of Florida, 572 Newell Drive, Gainesville, FL, 32611, USA.
Naim MontazeriFood Science and Human Nutrition Department, University of Florida, 572 Newell Drive, Gainesville, FL, 32611, USA. nmontazeri@ufl.edu.

Funding

U.S. Department of Agriculture 7007944 (S1077)U.S. Department of Agriculture FLA-FOS-006304/proposal no. 2022-09032
6 · The paper itself

Abstract

Human norovirus (HuNoV) is the primary cause of gastroenteritis globally. Due to the lack of a reliable cultivation system, RT-qPCR is a gold standard technique for the detection and quantification of HuNoV. However, the inability of PCR to differentiate between infectious from non-infectious particles remains a significant limitation. This study aims to address this limitation by exploring the relationship between culture-based (plaque assay and TCID

Indexed as

Caliciviridae InfectionsNorovirusReal-Time Polymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionGastroenteritisHumansRNA, ViralViral Plaque AssayRNA, ViralFood safetyInfectivity assessmentNorovirusPublic healthSurrogateTulane virus

Identifiers

PMID40057626
PMCPMC11890344

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.