ArticleNature communications2025
A multicenter cohort study of thyroidectomy-related decision regret in patients with low-risk papillary thyroid microcarcinoma.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Integrated Ultrasound Features, Cytologic Subclassification, and Systemic Inflammatory Markers for Predicting Malignancy in Bethesda III Thyroid Nodules.Journal of clinical medicine · 2026Article
- Factors associated with early complete resolution after radiofrequency ablation for low-risk papillary thyroid microcarcinoma: a dual-center retrospective study.European radiology · 2026Article
- Shared Decision-Making for Determining Treatment Strategies in Low-Risk Thyroid Cancer: Protocol of a Multicenter Cluster-Randomized Trial (MAeSTro-SDM).Journal of Korean medical science · 2026Article
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- Evolving Practices in Low-Risk Papillary Thyroid Cancer: Impact of the 2015 ATA Guidelines.Current oncology (Toronto, Ont.) · 2026Article
- Development and Validation of a Predictive Model for Postoperative Nausea and Vomiting in Thyroid Cancer Patients: A Retrospective Case-Control Study.Journal of multidisciplinary healthcare · 2026Article
- Diagnostic Performance of the ACR TI-RADS, C-TIRADS, K-TIRADS, and EU TI-RADS Classification Systems for Thyroid Micronodules: A Multicenter Prospective Study.International journal of general medicine · 2026Article
- Risk factors for central lymph node metastasis in papillary thyroid microcarcinoma: a simplified risk scoring system.Frontiers in endocrinology · 2026Article
- Integrating Ultrasound and Clinicopathologic Characteristics to Predict the Invasive Papillary Thyroid Carcinoma Among Indeterminate Thyroid Nodules.Cancer management and research · 2026Article
- Risk Stratification in Papillary Thyroid Microcarcinoma: Clinical Features Predicting Multifocality, Lymph Node Metastasis, and Recurrence - A Retrospective Cohort Study.Cancer management and research · 2026Article
- Comparative Outcomes of Microwave Ablation Versus Surgery for Papillary Thyroid Microcarcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Apparent Diffusion Coefficient as a Predictor of Microwave Ablation Response in Thyroid Nodules: A Prospective Study.Diagnostics (Basel, Switzerland) · 2025Article
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- Review
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- Machine Learning for Thyroid Cancer Detection, Presence of Metastasis, and Recurrence Predictions-A Scoping Review.Cancers · 2025Review
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- Traditional Chinese Medicine Treatment of Thyroid Cancer: A Review.International journal of general medicine · 2025Review
- Treatment preferences in low-risk papillary thyroid microcarcinoma: a discrete choice experiment.Frontiers in public health · 2025Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The level of thyroidectomy-related regret in patients with clinically low-risk papillary thyroid microcarcinoma (PTMC) and the determinants of decision regret are largely unknown. Here, we show that 319 (24.2%) of those who undergo thyroidectomy and 4 (3.4%) who undergo active surveillance (AS) express heightened regret based on validated decision regret scale (DRS) scores in the first online survey (P < 0.001). Multivariable analysis and the second online survey for patients with heightened regret confirm that postoperative lower thyroid cancer-specific quality of life (QoL) (scar and psychology) (75.5%) is the most common factor for heightened regret of thyroidectomy, followed by preoperative understanding of disease [not at all] (15.0%), presentation of complications (3.8%) and other factors (5.7%). These results highlight that more caution should be exercised when low-risk PTMC patients are scheduled for thyroidectomy. Information about the various treatments for clinically low-risk PTMC, the risk of thyroidectomy and postoperative QoL should be fully communicated during initial counseling.
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