ArticleIndian heart journal
Prevalence of periodontitis in chronic heart failure patients and its relationship with NT-ProBNP: A cross-sectional study.
Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Effects of Sacubitril Valsartan Combined With Vericiguat on NT-proBNP and CK-MB Levels in Patients With Chronic Heart Failure.Journal of applied toxicology : JAT · 2026Trial
- Association between periodontitis and heart failure: Mechanisms and clinical implications (Review).Molecular medicine reports · 2026Review
- Correlation analysis of Serum NT-pro-BNP, IGFBP-7 and CTRP12 levels in chronic heart failure patients.Journal of medical biochemistry · 2026Article
- Diagnostic value and risk correlation of serum heart-type fatty acid-binding protein (H-FABP) and osteoprotegerin (OPG) in chronic heart failure.Journal of medical biochemistry · 2026Article
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Authors and funding
7 authors.
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Abstract
backgroundPeriodontal disease has been associated with chronic heart failure (CHF) and may be an indicator of high risk of adverse cardiovascular outcomes. To date, only few studies have been done and none from India regarding the association of periodontal disease in heart failure patients. So, this study was done to assess the prevalence of periodontitis in CHF patients and its correlation with N-terminal pro brain natriuretic peptide (NT- ProBNP). MATERIALS AND
methodIn this study, 154 patients with stable CHF with left ventricular ejection fraction of less than 40 % were enrolled. All subjects underwent cardiologic and dental evaluations. NT pro-BNP level was measured in all patients. The periodontal screening index was used to quantify the degree of periodontal disease.
resultsGingivitis, moderate periodontitis, and severe periodontitis were present in 48 (31.2 %), 82 (53.2 %), and 24 (15.5 %) patients, respectively. In individuals under the age of 75 years, the study found a significant association between moderate and severe periodontitis and elevated NT-proBNP levels (p < 0.05). The comparison between gingivitis and moderate/severe periodontitis was statistically significant in post hoc analysis.
conclusionCHF patients exhibit a high prevalence of moderate and severe periodontitis. This study highlights a significant association between periodontitis severity and elevated NT-proBNP in CHF patients, underscoring a potential cardiac impact. Further research is warranted to deepen our understanding of this relationship.
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