Evidence map›Paper›PMID 40057187›Full record

ArticleThe journal of allergy and clinical immunology. In practice2025

Life Stressors, Resilience Resources, and Asthma Among Adults in the Hispanic Community Health Study/Study of Latinos.

Yueh-Ying Han, Kristina Gaietto, Wei Chen, Krista M Perreira, Eyal Oren, Amber Pirzada, Olga Garcia-Bedoya, Robert Kaplan, Carmen R Isasi, Juan C Celedón

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Article in The journal of allergy and clinical immunology. In practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Update on environmental determinants of allergic diseases.The Journal of allergy and clinical immunology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yueh-Ying HanDivision of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Kristina GaiettoDivision of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Wei ChenDivision of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Krista M PerreiraDepartment of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.
Eyal OrenDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, Calif.
Amber PirzadaInstitute for Minority Health Research, University of Illinois College of Medicine, Chicago, Ill.
Olga Garcia-BedoyaDivision of Academic Internal Medicine, University of Illinois College of Medicine, Chicago, Ill.
Robert KaplanPublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Wash; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Wash.
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Juan C CeledónDivision of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa. Electronic address: juan.celedon@chp.edu.

Funding

Nasal epithelial epigenomics and transcriptomics and asthma in Hispanic adultsR01HL152475 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS, ISASI, CARMEN R. · 2021 to 2025
$3.4M
Exposure to violence during childhood and Th2-high asthma in young Puerto Rican adultsR01HL168539 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Juan Carlos Celedon · 2023 to 2026
$2.6M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 HL152475NHLBI NIH HHS R01 HL168539
6 · The paper itself

Abstract

backgroundWhether life stressors and resiliency interact on asthma risk in adults is largely unknown.

objectiveTo examine life stressors, resiliency, and asthma in Hispanic/Latino adults.

methodsThis is a cross-sectional study of 4747 adults aged 18 to 74 years in the Sociocultural Ancillary Study of the Hispanic Community Health Study/Study of Latinos. Participants completed questionnaires on life stressors (adverse childhood experiences [ACE], traumatic stress exposure (TSE), and chronic stressors [for ≥6 months]) and resilience resources (family cohesion, perceived social support, and spiritual well-being). Logistic regression was used for the multivariable analyses of current asthma and current asthma symptoms.

resultsAny ACE and any chronic stressor were associated with 54% to 69% increased odds of asthma and asthma symptoms in all individuals, with stronger associations for ACE in men and for chronic stressors in women. In a separate analysis, high family cohesion and high spiritual well-being were each associated with 35% to 36% reduced odds of asthma symptoms. There was suggestive evidence of interactions: any TSE was associated with increased odds of asthma in adults with low family cohesion (adjusted odds ratio [aOR] = 2.40, 95% confidence interval [CI] = 1.01-5.73) but not in others, and any chronic stressor was associated with increased odds of asthma symptoms in adults with low spiritual well-being (aOR = 2.24, 95% CI = 1.20-4.20) but not in others.

conclusionsIn Hispanic/Latino adults, ACE and chronic stress were associated with higher odds of asthma or asthma symptoms, whereas family cohesion and spiritual well-being were linked to lower odds of asthma or asthma symptoms. Further, resiliency may interact with life stressors on asthma.

Indexed as

AsthmaHispanic or LatinoResilience, PsychologicalStress, PsychologicalAdolescentAdultAdverse Childhood ExperiencesAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSocial SupportSurveys and QuestionnairesUnited StatesAdverse childhood experiencesAsthmaAsthma symptomsChronic stressHispanic/Latino adultsResilience resourcesTraumatic stress

Identifiers

PMID40057187
PMCPMC12146061

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.