Evidence map›Paper›PMID 40056721›Full record

ArticleBreast (Edinburgh, Scotland)2025

Fertility preservation in young breast cancer patients: A nationwide survey on knowledge, attitudes, and practices among breast surgical healthcare providers in China.

Xiaoling Yuan, Jingdan Li, Nan Zhang, Jiayi Peng, Xiaoran Yang, Wen Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in Breast (Edinburgh, Scotland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoling YuanSchool of Nursing, Shanghai Jiao Tong University, 227 South Chongqing Road, Shanghai, ZIP 200025, China. Electronic address: xiaolingy@sjtu.edu.cn.
Jingdan LiDepartment of Breast Surgery, Lishui People's Hospital of Wenzhou Medical University, 15 Dazhong Street, Lishui City, Zhejiang Province, ZIP 323000, China; Institute of Breast Oncology, Lishui University Medical College, 15 Dazhong Street, Lishui City, Zhejiang Province, ZIP 323000, China. Electronic address: lijingdan@foxmail.com.
Nan ZhangComprehensive Breast Center, Ruijin Hospital Affiliated to Shanghai JiaoTong University, School of Medicine, 197 Rui Jin Er Road, Shanghai, ZIP 200025, China. Electronic address: zn21076@rjh.com.cn.
Jiayi PengSchool of Nursing, Shanghai Jiao Tong University, 227 South Chongqing Road, Shanghai, ZIP 200025, China. Electronic address: pjy129116@sjtu.edu.cn.
Xiaoran YangSchool of Nursing, Shanghai Jiao Tong University, 227 South Chongqing Road, Shanghai, ZIP 200025, China. Electronic address: richardyang@sjtu.edu.cn.
Wen LiAssisted Reproduction Center, International Peace Maternal and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, 910 Hengshan Road, Shanghai, ZIP 200030, China. Electronic address: liwen@shsmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFertility preservation (FP) is a critical concern for young breast cancer (YBC) patients receiving gonadotoxic treatments. Breast surgical healthcare providers (HCPs) play a pivotal role in discussing FP options and facilitating timely referrals. This study aimed to assess the knowledge, attitudes, and practices of breast surgical HCPs in China regarding FP, identify barriers to FP discussions, and examine factors influencing referral practices.

methodsA nationwide cross-sectional survey was conducted from March to June 2023 among board-certified breast surgeons and nurses across China using a 24-item questionnaire. Participants were recruited via WeChat through BestOnco, a professional platform for oncology HCPs. The survey assessed FP knowledge, attitudes, clinical practices, and perceived barriers. Multivariate logistic regression was performed to determine factors associated with FP referral practices.

resultsA total of 355 valid responses were analyzed. The mean FP knowledge score was 6.05 ± 1.94 (range 0-10), with 49.3 % of HCPs never consulting FP guidelines. While 82.8 % expressed a favorable attitude toward FP, only 42.3 % routinely discussed FP options, and 44.7 % referred patients to reproductive specialists. Major barriers included poor prognosis concerns (87.0 %), treatment urgency (67.9 %), and financial burden (60.0 %). Multivariate analysis revealed that higher FP knowledge (OR = 1.23, p < 0.0001), longer clinical experience (OR = 2.93, p = 0.001), and hospital-based FP integration (OR = 1.83, p < 0.0001) were significant predictors of referral.

conclusionsNotable gaps were identified in FP knowledge, discussions, and referrals among breast surgical HCPs in China. Targeted FP training programs, culturally informed shared decision-making strategies, and oncofertility navigation systems are recommended to enhance FP service delivery and improve patient outcomes.

Indexed as

Attitude of Health PersonnelBreast NeoplasmsFertility PreservationHealth Knowledge, Attitudes, PracticeSurgeonsAdultChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPractice Patterns, Physicians'Referral and ConsultationSurveys and QuestionnairesYoung AdultBreast cancerChinaFertility preservationHealthcare providersSurgical team

Identifiers

PMID40056721
PMCPMC11930796

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.