ArticleJournal of fluorescence2025
Enhanced Intracellular Delivery of Curcumin Using Polymeric Nanocarriers: A Natural Photosensitizing Agent for Anti-Cancer Photodynamic Therapy.
Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Targeting Cancer Stem Cells with Phytochemicals: Molecular Mechanisms and Therapeutic Potential.Biomedicines · 2026Review
- Curcumin-Loaded Nanomaterials as Carriers for Photodynamic Therapy Against Cancers.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Curcumin ranks among the extensively investigated Phytocompounds with a wide array of therapeutic properties. It has bioactive and photoactive properties that enhance its potential as an anti-cancer agent. However, poor solubility and low bioavailability are associated with it which hinders its applications. To address the limitations related to free curcumin (CUR), the present study focuses on the synthesis of curcumin-loaded poly lactic-co-glycolic acid nanoparticles (CUR NPs). The single emulsion solvent evaporation technique was used to synthesize CUR NPs with an average size of 187 nm and a zeta potential of -13.3 mV. Photophysical properties, drug loading efficiency, and drug release profile of synthesized CUR NPs were studied. Confocal fluorescence imaging was employed to study the cellular uptake of both formulations of CUR. The In-vitro investigation was conducted using BT-474 human breast cancer cells to evaluate the dark and phototoxic effect of both variants of curcumin (free CUR and CUR NPs). The cytotoxicity was quantified through half-maximal inhibitory concentration (IC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.