ReviewArchives of dermatological research2025
Applications of reflectance confocal microscopy in photoaging and aesthetic conditions: skin characterization and treatment monitoring.
Review in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Multimodal Non-Invasive Skin Imaging in Dermatology: Current Modalities, Clinical Applications, and Future Integration.Diagnostics (Basel, Switzerland) · 2026Review
- Label-free visualization and quantitative analysis of Far UV-C skin safety with dynamic optical coherence tomography with subcellular resolution.Biomedical optics express · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reflectance confocal microscopy (RCM) is an in-vivo, non-invasive imaging modality that provides a high-resolution image of the epidermis and upper dermis. RCM has been utilized as a diagnostic aid for several inflammatory, infectious, and malignant skin conditions; however, its use for clinical and aesthetic skin purposes has not been well established. The purpose of this review is to describe the landscape of RCM utilization for the application of aesthetic skin conditions. A comprehensive literature search was conducted using PubMed using the search terms "reflectance confocal microscopy cosmetic", and "reflectance confocal microscopy aesthetic". The search was limited to clinical and animal studies published in English in the last 10 years. RCM must have been utilized to measure an aesthetic dermatological outcome to be eligible for the review. After data abstraction, a total of 46 studies that met the inclusion criteria were identified. The most common utilization of RCM for cosmetic conditions included treatment monitoring and skin morphologic characterization. The primary skin conditions evaluated included skin aging, pigmentation, skin dryness, irritated, and sensitive skin related conditions. Treatment monitoring was primarily conducted for topical agents for skin hydration, skin UV protection, acne, skin dryness, and skin pigmentation purposes. Identification of histo-structural correlations with aesthetic skin conditions may pave the way for future aesthetic drug development. As the popularity of cosmetic dermatologic procedures continues to increase, utilization of RCM for skin characterization and treatment monitoring may be beneficial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.