Evidence map›Paper›PMID 40056073›Full record

ArticleInternal medicine journal2025

Filling the gaps to empower regional centres to manage myelodysplastic syndrome and acute myeloid leukaemia leading to wider cancer healthcare delivery and access to clinical trials.

Michael Ashby, Shaun Fleming, Andrew Spencer, Anne Woollett, Tricia Wright

Abstract readCase Reports
In one paragraph

Article in Internal medicine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael AshbyDepartment of Cancer Services, Latrobe Regional Health, Traralgon, Victoria, Australia.ORCID 0000-0001-8653-4844
Shaun FlemingDepartment of Clinical Haematology, Alfred Health, Melbourne, Victoria, Australia.
Andrew SpencerDepartment of Clinical Haematology, Alfred Health, Melbourne, Victoria, Australia.
Anne WoollettTrialHub, Department of Research, Alfred Health, Melbourne, Victoria, Australia.
Tricia WrightDepartment of Cancer Services, Latrobe Regional Health, Traralgon, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of patients with haematological malignancies in rural and regional Australia is different to that in metropolitan centres due to many factors. Lower-intensity and easier-to-access treatments that are now available for acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) have improved the deliverability of treatment options for these disorders. Despite the challenges, urgent work is required to allow the care and outcomes of these patients to mirror those living in metropolitan centres.

aimsTo highlight the challenges in management of AML and MDS in regional Victoria.

methodsFour clinical cases describing the difficulties faced in the management of AML/MDS patients in regional Victoria.

resultsWe describe limitations in inpatient services, supportive care, blood product access and both specialised diagnostics and specialist workforce. Access to clinical trials is limited but vital to allow the availability of all therapeutic options.

conclusionsLimitations in management of AML/MDS patients exist in regional centres. We utilised focused clinical fellows in a partnership between Latrobe Regional Health and Alfred Health in Victoria to improve treatment options for these patients. Moreover, we demonstrate future areas of focus, which will further enable rural and regional healthcare providers to bridge the gap in the care of patients with haematological malignancies.

Indexed as

Delivery of Health CareHealth Services AccessibilityLeukemia, Myeloid, AcuteMyelodysplastic SyndromesAgedClinical Trials as TopicFemaleHumansMaleVictoriaaccessibility of health serviceacute myeloid leukaemiahealth resourcemyelodysplastic syndromerural health

Identifiers

PMID40056073
PMCPMC12077582

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.