ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Task-Oriented Biomedical Microrobots: Access, Working Environment, Actuation, Body Design, Detection and Control.Micromachines · 2026Review
- Systemic-to-local nanorobot thrombolysis.Science advances · 2026Article
- Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Micro/Nanorobotic Systems for Imaging-Guided Closed-Loop Thrombus Recanalization.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- Advancements and challenges of nanorobots in surgical medicine: design, applications, and interdisciplinary integration.Frontiers in bioengineering and biotechnology · 2026Review
- MRI-Guided Magnetic Micro/Nanorobots for Precision Neurotherapeutics: From Intelligent Navigation and BBB Penetration to Clinical Translation.International journal of nanomedicine · 2026Review
- Ultrasound-actuated platelet mimetic nanomotors enable targeted piezocatalytic ROS storm for precision thrombolysis.Journal of nanobiotechnology · 2025Article
- Reconfigurable robust microrobot collectives with large force output enabled by gradient magnetic fields.Science advances · 2025Article
- A magnetically actuated microcatheter with soft rotatable tip for enhanced endovascular access and treatment efficiency.Science advances · 2025Article
- Untethered miniature robots for minimally invasive thrombus treatment: From bench to clinical trials.Innovation (Cambridge (Mass.)) · 2025Review
- Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Micro/nano-scale robotic devices are emerging as a cutting-edge approach for precision intravascular therapies, offering the potential for highly targeted drug delivery. While employing micro/nanorobotics for stroke treatment is a promising strategy due to its ability to localize therapy and minimize drug dosage, current methods require prolonged treatment durations, increasing the risk of nerve tissue necrosis from extended hypoxia. Here a programmable colloidal microswarm capable of rapidly detaching blood clots from the vessel wall is developed, enabling swift recanalization without the need for complete clot degradation. More importantly, the detached clot debris, despite their random shapes, functions as magnetic "debris-robots" and can be efficiently propelled through helical swimming within flowing vessels, followed by retrieval using catheter suction. The entire process-including catheter delivery, controlled locomotion, clot detachment, and retrieval-can be completed in approximately half an hour, significantly saving time compared to the critical "Golden 6 hours" window for stroke treatment. This retrieval procedure greatly minimizes nanoparticle exposure in the bloodstream and lowers the risk of secondary clotting in distal vessels, marking a significant advancement in robotic-assisted thrombolysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.