ArticleJournal of veterinary internal medicine
Daily Heart Rate Variability in Dogs With Atrial Fibrillation.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundDaily variability of heart rate in 24-h Holter recordings in dogs with atrial fibrillation (AF) receiving antiarrhythmic drugs (AAD) is unknown and could influence medical decisions. HYPOTHESIS/
objectivesDogs with AF, Holter-derived mean heart rate (meanHRHolter) over 24 h is not significantly different from a subsequent, consecutive 24-h period. ANIMALS: Twenty-five dogs with AF.
methodsProspective, descriptive, multicenter study. MeanHRHolter rate and ventricular arrhythmias (VAs) were prospectively analyzed after starting AAD. Clinically relevant difference (defined as ≥ 10 bpm in the meanHRHolter), success of rate control (defined as meanHRHolter ≤ 125 bpm). A Bland-Altman analysis and intra-class correlation coefficient (ICC) were calculated to compare two consecutive 24-h Holter recordings. VAs percentage difference [(maximum daily value-minimum daily value)/maximum daily value × 100] and grading variability between recordings were also investigated.
resultsSmall BIAS with ICC 0.98 (95% confidence interval [CI] 0.95-0.99) on meanHRHolter with no statistical difference between two consecutive 24-h Holter recordings (95% CI [-2.84-2.92], degree of freedom 24, p = 0.98). Only 2/25 dogs (8%; 95% CI [2%-25%]) had clinically significant variation, while 1/25 (4%; 95% CI [0%-20%]) dogs showed different classifications in the success of rate control between the consecutive recordings. The VAs percentage difference was 52%, with 7/25 (28%; 95% CI [14%-47%]) dogs showing a VAs grading difference of ≥ 2. CONCLUSION AND CLINICAL IMPORTANCE: The daily heart rate variability in dogs with AF receiving AAD is low, suggesting that a single 24-h Holter recording is adequate to assess rate control. Daily variability might be an important consideration when assessing VAs in dogs with concomitant AF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.