Evidence map›Paper›PMID 40055869›Full record

Observational studyJournal of the American Heart Association2025

Association of Cardiologist Clinic Visits With Cardiovascular Primary Prevention Outcomes Among People With HIV From Underrepresented Racial and Ethnic Groups in the Southern United States.

Matthew S Durstenfeld, C Larry Hill, Robert M Clare, Karen Chiswell, Gretchen Sanders, Shamea Gray, Joseph Vicini, Keith Marsolo, Nwora Lance Okeke, Eric G Meissner and 5 more

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04025125 (Pathways to Cardiovascular Disease Prevention and Impact of Specialty Referral in Underrepresented Racial/Ethnic Minorities With HIV), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04025125 completednot on this map

Pathways to Cardiovascular Disease Prevention and Impact of Specialty Referral in Underrepresented Racial/Ethnic Minorities With HIV (Coordinating Center)

TypeobservationalSponsorDuke UniversityRan2014 to 2020Enrolled2,039ConditionsHIV/AIDS, Cardiovascular Diseases
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Matthew S DurstenfeldDivision of Cardiology at Zuckerberg San Francisco General University of California San Francisco San Francisco CA USA.ORCID 0000-0002-7612-3352
C Larry HillDuke Clinical Research Institute Durham NC USA.
Robert M ClareDuke Clinical Research Institute Durham NC USA.
Karen ChiswellDuke Clinical Research Institute Durham NC USA.ORCID 0000-0002-0279-9093
Gretchen SandersDuke Clinical Research Institute Durham NC USA.ORCID 0000-0001-5061-7947
Shamea GrayDepartment of Medicine Duke University School of Medicine Durham NC USA.ORCID 0009-0006-7525-2829
Joseph ViciniDepartment of Medicine Vanderbilt University Medical Center Nashville TN USA.
Keith MarsoloDuke Clinical Research Institute Durham NC USA.ORCID 0000-0002-4416-1549
Nwora Lance OkekeDepartment of Medicine Duke University School of Medicine Durham NC USA.
Eric G MeissnerDivision of Infectious Diseases, Department of Microbiology and Immunology Medical University of South Carolina Charleston SC USA.ORCID 0000-0002-5240-7115
Kevin L ThomasDepartment of Medicine Duke University School of Medicine Durham NC USA.ORCID 0000-0002-0040-5396
Caryn G MorseDivision of Infectious Diseases Wake Forest Baptist Health Winston-Salem NC USA.ORCID 0000-0002-1177-4365
Gerald S BloomfieldDuke Clinical Research Institute Durham NC USA.ORCID 0000-0002-7176-1611
April C PettitDepartment of Medicine Vanderbilt University Medical Center Nashville TN USA.ORCID 0000-0001-8832-0866
Chris T LongeneckerDivision of Cardiology & Department of Global Health University of Washington Seattle WA USA.ORCID 0000-0002-9468-0179

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
The role of SMAD1 and SATB2 in colon patterningP20GM130457 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Hailong Zhang · 2020 to 2026
$18.7M
Pathways to cardiovascular disease prevention and impact of specialty referral in under-represented racial/ethnic minorities with HIVR01MD013493 · NIMHD · DUKE UNIVERSITY · PI BLOOMFIELD, GERALD SAMUEL · 2018 to 2022
$3.3M
Multi-level Social and Behavioral Determinants of Health and Missed HIV Healthcare Provider VisitsR01MH113438 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PETTIT, APRIL · 2018 to 2020
$1.3M
A Clinic-Based Behavioral Intervention to Reduce Cardiovascular Disease Risk in Persons Living with HIVK23HL137611 · NHLBI · DUKE UNIVERSITY · PI OKEKE, NWORA LANCE · 2018 to 2022
$895k
Low Cardiorespiratory Fitness and Chronotropic Incompetence inHIV: Risk Factors, Cardiovascular Implications, and Exercise Training as TreatmentK23HL172699 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Matthew Durstenfeld · 2024 to 2026
$593k
NHLBI NIH HHS K23 HL137611NHLBI NIH HHS K23 HL172699NIAID NIH HHS P30 AI110527NIGMS NIH HHS P20 GM130457NIMHD NIH HHS R01 MD013493NIMH NIH HHS R01 MH113438
6 · The paper itself

Abstract

backgroundPeople with HIV (PWH) have elevated cardiovascular risk. Underrepresented racial and ethnic groups in the southern United States are disproportionately affected, yet whether cardiology care for this at-risk group improves blood pressure and lipid control or prevents cardiovascular events is unknown. METHODS AND

resultsWe evaluated a cohort of PWH from underrepresented racial and ethnic groups who received HIV-related care at 4 centers in the southern United States during 2015 to 2018 with follow-up through 2020. Primary outcomes were blood pressure control (<140/90 mm Hg) and lipid control (low-density lipoprotein cholesterol ≤100 mg/dL) over 2 years and time to first major adverse cardiovascular event. Statistical analyses were adjusted for cohort/site and patient sociodemographic factors, HIV measures, and comorbidities. Among 3972 included PWH (median age, 47 years; 32.6% women) without diagnosed cardiovascular disease, 276 (6.9%) had a cardiology clinic visit. Cardiology visits were not associated with subsequent blood pressure control (adjusted odds ratio, 0.78 [95% CI, 0.49-1.24];

conclusionsAmong PWH from underrepresented racial and ethnic groups at elevated risk for cardiovascular disease, a cardiology clinic visit was not associated with risk factor improvement or reduced risk of a major adverse cardiovascular event. Our study suggests that seeing a cardiologist is not sufficient to promote cardiovascular health or prevent cardiovascular events among PWH, but with low confidence given the higher risk among those who had a cardiology visit.

Indexed as

CardiologistsCardiovascular DiseasesHIV InfectionsPrimary PreventionAdultBlood PressureEthnicityFemaleHumansMaleMiddle AgedRacial GroupsUnited Statescardiovascular diseases specialtyHIVoutcomesprimary prevention

Identifiers

PMID40055869
PMCPMC12132730

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.